Int J Hyperthermia. 2010 Feb;26(1):1-11. doi: 10.3109/02656730903492916.
A commercial diagnostic ultrasound scanner (Octoson) was modified for performing hyperthermia treatments. The temperature elevations were induced in tissues by four large, focused ultrasonic transducers whose common focal zone was scanned along a computer controlled path as determined from B-scan images. The system is described and the results of preliminary tests demonstrating some of its capabilities are given. Extensive tests with canine thighs and kidneys were performed. The blood flow to the kidneys was controllable, and thus tumours having different blood perfusion rates could be simulated. The results showed that the system is capable of inducing a local temperature maximum deep in tissues (up to 10 cm was tested) and that tissues with high perfusion rates could be heated.
一台商用诊断超声扫描仪（Octoson）经过改装，可用于进行热疗。通过四个大型聚焦超声换能器在组织中产生温升，这些换能器的公共焦点区域沿着计算机控制的路径扫描，该路径是根据 B 扫描图像确定的。本文对该系统进行了描述，并给出了初步测试结果，展示了其部分功能。我们对犬的大腿和肾脏进行了广泛的测试。肾脏的血流是可控制的，因此可以模拟具有不同血流灌注率的肿瘤。结果表明，该系统能够在组织深处产生局部温度最大值（最高可达 10 厘米），并且高灌注率的组织可以被加热。
