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[肠道病毒引起的脑膜炎。成人几例散发病例的临床和病毒学研究]

[Meningitis caused by enteroviruses. Clinical and virological study of several sporadic cases in adults].

作者信息

Voiculescu M, Brăiloiu-Ciugarin M

出版信息

Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Bacteriol Virusol Parazitol Epidemiol. 1977 Jul-Sep;22(3):149-62.

PMID:201003
Abstract

In the course of seven years (1968--1974) viral investigations were carried out in 212 casese of meningitis; predominantly Coxsackie viruses and sometimes ECHO viruses were isolated from 80 cases (37.73%). No polioviruses were isolated. Analysis of the clinical data (onset, general conidtion, evolution, complications, psychical, renal and cardiac disturbances etc.) revealed the severe aspect of these cases. The aspect and evolution of the cerebrospinal fluid showed the presence in almost 25% of the cases of an increased number of cellular elements of more than 1 000/mm3 and albumin sometimes far above normal values with a slow return (3--4 weeks). The complex therapy applied in more than half the cases demonstrates the necessity of attentive follow up of these cases of viral meningitis.

摘要

在七年(1968 - 1974年)期间,对212例脑膜炎病例进行了病毒学调查;从80例(37.73%)中主要分离出柯萨奇病毒,有时也分离出埃可病毒。未分离出脊髓灰质炎病毒。对临床资料(发病、一般状况、病情演变、并发症、精神、肾脏和心脏紊乱等)的分析显示了这些病例的严重程度。脑脊液的情况和演变表明,近25%的病例中细胞成分数量增加超过1000/mm³,白蛋白有时远高于正常值,且恢复缓慢(3 - 4周)。超过半数病例所采用的综合治疗表明,对这些病毒性脑膜炎病例进行密切随访是必要的。

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