Department of Pediatric Immunology, Uludag University School of Medicine, Bursa, Turkey.
J Trop Pediatr. 2010 Oct;56(5):359-62. doi: 10.1093/tropej/fmp140. Epub 2010 Jan 25.
Leukocytoclastic vasculitis is a rare complication of the use of granulocyte colony-stimulating factor (G-CSF). We present two cases of severe congenital neutropenia (SCN) associated with GCSF use. It is reported that skin rashes and biopsy findings of leukocytoclastic vasculitis following the use of G-CSF.
白细胞碎裂性血管炎是使用粒细胞集落刺激因子(G-CSF)的罕见并发症。我们报告了两例与 GCSF 使用相关的严重先天性中性粒细胞减少症(SCN)病例。据报道,使用 G-CSF 后会出现皮疹和白细胞碎裂性血管炎的活检结果。