心血管危险因素负担、亚临床动脉粥样硬化与宗教信仰维度的心血管事件发生：动脉粥样硬化的多民族研究。
Burden of cardiovascular risk factors, subclinical atherosclerosis, and incident cardiovascular events across dimensions of religiosity: The multi-ethnic study of atherosclerosis.
机构信息
Department of Preventive Medicine, Northwestern University, Chicago, IL 60611, USA.
出版信息
Circulation. 2010 Feb 9;121(5):659-66. doi: 10.1161/CIRCULATIONAHA.109.879973. Epub 2010 Jan 25.
BACKGROUND
Religious involvement has been associated with improved health practices and outcomes; however, no ethnically diverse community-based study has examined differences in cardiac risk factors, subclinical cardiovascular disease, and cardiovascular disease (CVD) events across levels of religiosity.
METHODS AND RESULTS
We included 5474 white, black, Hispanic, and Chinese participants who attended examination 2 of the National Heart, Lung, and Blood Institute's Multi-Ethnic Study of Atherosclerosis (MESA). We compared cross-sectional differences in cardiac risk factors and subclinical CVD and longitudinal CVD event rates across self-reported levels of religious participation, prayer/meditation, and spirituality. Multivariable-adjusted regression models were fitted to assess associations of measures of religiosity with risk factors, subclinical CVD, and CVD events. MESA participants (52.4% female; mean age, 63) with greater levels of religious participation were more likely to be female and black. After adjustment for demographic covariates, participants who attended services daily, compared with never, were significantly more likely to be obese (adjusted odds ratio 1.57, 95% confidence interval [CI] 1.12 to 1.72) but less likely to smoke (adjusted odds ratio 0.39, 95% CI 0.26 to 0.58). Results were similar for those with frequent prayer/meditation or high levels of spirituality. There were no consistent patterns of association observed between measures of religiosity and presence/extent of subclinical CVD at baseline or incident CVD events during longitudinal follow-up in the course of 4 years.
CONCLUSIONS
Our results do not confirm those of previous studies associating greater religiosity with overall better health risks and status, at least with regard to CVD. There was no reduction in risk for CVD events associated with greater religiosity.
背景
宗教参与与改善健康行为和结果有关；然而，没有一项基于种族多样性的社区研究检验了不同宗教参与程度与心脏风险因素、亚临床心血管疾病和心血管疾病（CVD）事件之间的差异。
方法和结果
我们纳入了 5474 名白种人、黑种人、西班牙裔和华裔参与者，他们参加了国家心肺血液研究所多民族动脉粥样硬化研究（MESA）的第 2 次检查。我们比较了自我报告的宗教参与、祈祷/冥想和灵性水平的横断面心脏风险因素和亚临床 CVD 差异以及 CVD 事件发生率。多变量调整回归模型用于评估宗教性测量与风险因素、亚临床 CVD 和 CVD 事件之间的关联。MESA 参与者（52.4%为女性；平均年龄 63 岁）中，宗教参与程度较高的人更可能为女性和黑人。在调整人口统计学协变量后，与从不参加相比，每天参加服务的参与者更有可能肥胖（调整后的优势比 1.57，95%置信区间[CI] 1.12 至 1.72），但不太可能吸烟（调整后的优势比 0.39，95%CI 0.26 至 0.58）。对于经常祈祷/冥想或高灵性水平的参与者，结果相似。在 4 年的纵向随访过程中，没有观察到宗教性测量与亚临床 CVD 的存在/严重程度或心血管疾病事件之间存在一致的关联模式。
结论
我们的结果与以前将更大的宗教性与整体更好的健康风险和状况相关联的研究不一致，至少与 CVD 无关。与更大的宗教性相关的 CVD 事件风险没有降低。
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