Kobayashi Daiki, Kuga Hironori, Shimbo Takuro
Division of General Internal Medicine, Department of Medicine, Tokyo Medical University Ibaraki Medical Center, Ibaraki, Japan.
Fujita Health University, Toyoake, Japan.
Biopsychosoc Med. 2023 Feb 9;17(1):3. doi: 10.1186/s13030-023-00265-6.
The aim of this study was to evaluate the association between the degree of religiosity and subsequent fractures and a decrease in bone mineral density in a Japanese population.
We conducted a retrospective longitudinal study at St. Luke's International Hospital in Tokyo, Japan, from 2005 to 2018. All participants who underwent voluntary health check-ups were included. Our outcomes were any fractures and the change in T-score from baseline to each visit. We compared these outcomes by the self-reported degree of religiosity (not at all; slightly; somewhat; very) and adjusted for potential confounders.
A total of 65,898 participants were included in our study. Their mean age was 46.2(SD:12.2) years, and 33,014(50.1%) were male. During a median follow-up of 2,500 days (interquartile range (IQR):987-3,970), 2,753(4.2%) experienced fractures, and their mean delta T-score was -0.03%(SD:18.3). In multivariable longitudinal analyses, the slightly religious group had a statistically lower adjusted odds ratio (AOR) for a fracture than the nonreligious group(AOR:0.81,95% confidence interval(CI):0.71 to 0.92).
We demonstrated that slightly religious people, but not somewhat or very religious people, had a lower incidence of fracture than nonreligious individuals, although the T-scores were similar regardless of the degree of religiosity.
本研究旨在评估日本人群中宗教虔诚程度与随后发生骨折及骨密度降低之间的关联。
2005年至2018年,我们在日本东京圣路加国际医院进行了一项回顾性纵向研究。纳入所有接受自愿健康检查的参与者。我们的结局指标是任何骨折情况以及从基线到每次随访时T值的变化。我们根据自我报告的宗教虔诚程度(完全不;轻微;有些;非常)比较这些结局,并对潜在混杂因素进行了校正。
我们的研究共纳入65898名参与者。他们的平均年龄为46.2岁(标准差:12.2),男性有33014名(50.1%)。在中位随访2500天(四分位间距(IQR):987 - 3970)期间,2753名(4.2%)发生了骨折,他们的平均T值变化为-0.03%(标准差:18.3)。在多变量纵向分析中,宗教虔诚程度为轻微的组发生骨折的校正比值比(AOR)在统计学上低于无宗教信仰的组(AOR:0.81,95%置信区间(CI):0.71至0.92)。
我们证明,宗教虔诚程度为轻微的人群,而非有些或非常虔诚的人群,骨折发生率低于无宗教信仰者,尽管无论宗教虔诚程度如何,T值相似。