Liu Lin-Lin, Feng Mao-Ling, Wang Li-Ning, Li Xiao-Li, Yao Li
Department of Nephrology, The First Affiliated Hospital of China Medical University, People's Republic of China.
J Clin Apher. 2010;25(2):74-6. doi: 10.1002/jca.20227.
Adult onset Still's disease (AOSD) is a rare systemic inflammatory disorder of unknown etiology and pathogenesis. The disease is characterized by typical spiking fever with evanescent rash, sore throat, polyarthralgias or polyarthritis, and involvement of various organs. Most of the reported cases with liver involvement occurred during the period of treatment with hepatotoxic drugs, whereas AOSD associated autoimmune hepatitis (AIH) is extremely rare. AIH may be an indicator of the poor prognosis of AOSD. Herein we describe a case of successful treatment with plasma exchange for AOSD-associated AIH.
成人斯蒂尔病（AOSD）是一种病因和发病机制不明的罕见全身性炎症性疾病。该疾病的特征为典型的弛张热伴一过性皮疹、咽痛、多关节痛或多关节炎，以及多器官受累。大多数报道的肝脏受累病例发生在使用肝毒性药物治疗期间，而AOSD相关的自身免疫性肝炎（AIH）极为罕见。AIH可能是AOSD预后不良的一个指标。在此，我们描述一例采用血浆置换成功治疗AOSD相关AIH的病例。
