巴雷特食管的形态与糜烂性食管炎的患病率有关。
Shape of Barrett's epithelium is associated with prevalence of erosive esophagitis.
机构信息
Gastroenterology Division, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan.
出版信息
World J Gastroenterol. 2010 Jan 28;16(4):484-9. doi: 10.3748/wjg.v16.i4.484.
AIM
To test the hypothesis that the shape and length of Barrett's epithelium are associated with prevalence of erosive esophagitis.
METHODS
A total study population comprised 869 patients who underwent endoscopy during a health checkup at our hospital. The presence and extent of Barrett's epithelium were diagnosed based on the Prague C & M Criteria. We originally classified cases of Barrett's epithelium into two types based on its shape, namely, flame-like and lotus-like Barrett's epithelium, and into two groups based on its length, its C extent < 2 cm, and > or = 2 cm. Correlation of shape and length of Barrett's epithelium with erosive esophagitis was examined.
RESULTS
Barrett's epithelium was diagnosed in 374 cases (43%). Most of these were diagnosed as short-segment Barrett's epithelium. The prevalence of erosive esophagitis was significantly higher in subjects with flame-like than lotus-like Barrett's epithelium, and in those with a C extent of > or = 2 cm than < 2 cm.
CONCLUSION
Flame-like rather than lotus-like Barrett's epithelium, and Barrett's epithelium with a longer segment were more strongly associated with erosive esophagitis.
目的
检验假设，即巴雷特食管的形态和长度与糜烂性食管炎的患病率相关。
方法
本研究共纳入 869 名在我院体检时接受内镜检查的患者。巴雷特食管的存在和范围根据布拉格 C&M 标准进行诊断。我们最初根据其形态将巴雷特食管分为火焰状和莲花状巴雷特食管两种类型，并根据其长度将其分为两组，即 C 段<2cm 和≥2cm。检查巴雷特食管的形态和长度与糜烂性食管炎的相关性。
结果
374 例（43%）被诊断为巴雷特食管。其中大多数被诊断为短节段巴雷特食管。与莲花状巴雷特食管相比，火焰状巴雷特食管和 C 段长度≥2cm 的患者中，糜烂性食管炎的患病率明显更高。
结论
与莲花状巴雷特食管相比，火焰状巴雷特食管，以及具有更长节段的巴雷特食管与糜烂性食管炎的相关性更强。
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