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保存剩余物:脐带血干细胞储存模式

Saving the leftovers: models for banking cord blood stem cells.

作者信息

Cogdell Kimberly J

机构信息

North Carolina Central University School of Law, USA.

出版信息

Issues Law Med. 2009 Fall;25(2):145-65.

PMID:20101907
Abstract

Each year there are over four million live births in the United States. Each birth produces umbilical cord blood stem cells, which are usually discarded. The author argues that rather than discarding the umbilical cord, this valuable resource of cord blood should be banked and used for research and therapeutic purposes. Umbilical cord blood could provide a solution to the critical need to find matching donors for hematopoietic transplants in patients who have no matching bone marrow donors. Creating a system of universal donation to a public bank will greatlyincrease the number of donors and therefore, the number of matches for patients. Such a system will facilitate the development and use of new technologies and transplant procedures, while providing an opportunity for treatment to individuals who would otherwise not be able to find suitable donors.

摘要

在美国,每年有超过四百万例活产。每次分娩都会产生脐带血干细胞,而这些干细胞通常会被丢弃。作者认为,不应丢弃脐带,这种宝贵的脐带血资源应进行储存,并用于研究和治疗目的。对于那些没有匹配骨髓供体的患者而言,脐带血可为寻找造血干细胞移植匹配供体的迫切需求提供解决方案。建立一个向公共库进行普遍捐赠的系统将大大增加供体数量,从而增加患者找到匹配供体的数量。这样一个系统将促进新技术和移植程序的开发与应用,同时为那些否则无法找到合适供体的个人提供治疗机会。

相似文献

1
Saving the leftovers: models for banking cord blood stem cells.保存剩余物:脐带血干细胞储存模式
Issues Law Med. 2009 Fall;25(2):145-65.
2
Development of stem cells from umbilical cord blood and blood banking: "non-controversial" and "free of political and ethical debate"?脐带血干细胞的研发与血库:“毫无争议”且“不存在政治和伦理争论”?
J Law Med. 2012 Mar;19(3):490-6.
3
[Umbilical cord blood as a source of stem cells].[脐带血作为干细胞的来源]
Acta Med Croatica. 2006 Jun;60(3):215-25.
4
Umbilical cord stem cells.脐带干细胞
Obstet Gynecol. 2005 Dec;106(6):1393-407. doi: 10.1097/01.AOG.0000188388.84901.e4.
5
Umbilical cord blood transplantation: providing a donor for everyone needing a bone marrow transplant?脐带血移植:为每个需要骨髓移植的人提供供体?
South Med J. 1998 Sep;91(9):821-8.
6
Proposed policies and procedures for the establishment of a cord blood bank.建立脐带血库的拟议政策与程序。
Blood Cells. 1994;20(2-3):609-26.
7
Cord blood banking: a historical perspective.脐带血库:历史视角。
Br J Haematol. 2009 Oct;147(2):236-45. doi: 10.1111/j.1365-2141.2009.07827.x.
8
ACOG committee opinion number 399, February 2008: umbilical cord blood banking.美国妇产科医师学会委员会意见第399号,2008年2月:脐带血储存
Obstet Gynecol. 2008 Feb;111(2 Pt 1):475-7. doi: 10.1097/AOG.0b013e318166603c.
9
Ethnicity, equity and public benefit: a critical evaluation of public umbilical cord blood banking in Australia.
Bone Marrow Transplant. 2007 Oct;40(8):729-34. doi: 10.1038/sj.bmt.1705812. Epub 2007 Aug 13.
10
[Cord blood banking].[脐带血储存]
Acta Med Croatica. 2009 Jun;63(3):245-50.

引用本文的文献

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Ethical and legal considerations regarding the ownership and commercial use of human biological materials and their derivatives.关于人类生物材料及其衍生物的所有权和商业用途的伦理和法律考量。
J Blood Med. 2012;3:87-96. doi: 10.2147/JBM.S36134. Epub 2012 Aug 7.