Gao Bo, Wei Wei, Gong Min, Wang Li
School of Physical Science and Technology, Sichuan University, Sichuan Province Key Laboratory of Microelectronics, Chengdu 610064, China.
Guang Pu Xue Yu Guang Pu Fen Xi. 2009 Nov;29(11):2922-5.
The technology of non-invasive near-infrared spectral detection of biological tissue blood oxygen saturation has great research and application prospects, and has widespread clinical applications. However, the conventional finger oximeter only reflects local oxygen saturation values, and has limitations in the application. These oxygenation readings become unreliable or cease, too. In the present paper, a new method is described that the reflectance pulse oximetry with variable incident light intensity is employed to measure biological multilayer tissue. The photoplethysmographic (PPG) signals significantly change with the change in the incident light intensity in the experiment on the fingertip. Further analysis shows that the changes of the PPG signals correspond to the multilayer structure of finger. It means that the blood oxygen saturation of different tissue level must be calculated from the PPG signals. These features show that this method must be feasible.
生物组织血氧饱和度的无创近红外光谱检测技术具有很大的研究和应用前景，并且在临床上有广泛的应用。然而，传统的手指血氧仪仅反映局部血氧饱和度值，在应用中存在局限性。这些氧合读数也会变得不可靠或中断。在本文中，描述了一种新方法，即采用可变入射光强度的反射式脉搏血氧测定法来测量生物多层组织。在指尖实验中，光电容积脉搏波（PPG）信号随入射光强度的变化而显著变化。进一步分析表明，PPG信号的变化与手指的多层结构相对应。这意味着必须从PPG信号中计算出不同组织层的血氧饱和度。这些特征表明该方法是可行的。
