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禁食状态下人体血浆环磷酸腺苷浓度升高。

Increased plasma cyclic AMP concentrations in fasting man.

作者信息

Mjøos O D, Vik-Mo H, Henden T, Wang H

出版信息

Scand J Clin Lab Invest. 1977 Sep;37(5):439-42.

PMID:201022
Abstract

Plasma concentrations of adenosine 3', 5' monophosphate (cyclic AMP), free fatty acids (FFA), glycerol and glucose were measured after 24, 48 and 72 h fasting in healthy male students. There was a marked rise in plasma concentrations of cyclic AMP, FFA and glycerol from 24 to 48 h fasting with no further changes from 48 to 72 h fasting. Plasma glucose concentrations fell. After 72 h fasting, inhibition of adipose tissue lipolysis with a nicotinic acid analogue effected no significant change in plasma cyclic AMP concentrations, indicating that the elevated plasma nucleotide concentrations during fasting were not related to stimulation of lipolysis.

摘要

对健康男学生禁食24、48和72小时后的血浆3',5'-单磷酸腺苷(环磷酸腺苷)、游离脂肪酸(FFA)、甘油和葡萄糖浓度进行了测定。禁食24至48小时期间,血浆环磷酸腺苷、游离脂肪酸和甘油浓度显著升高,而禁食48至72小时期间则无进一步变化。血浆葡萄糖浓度下降。禁食72小时后,用烟酸类似物抑制脂肪组织脂解对血浆环磷酸腺苷浓度无显著影响,这表明禁食期间血浆核苷酸浓度升高与脂解刺激无关。

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