Senff H, Kunz R, Köllner A, Kunze J
Klinik für Dermatologie und Allergologie, St. Barbara-Hospital Duisburg.
Hautarzt. 1991 Jan;42(1):53-5.
Two female patients developed an allergic contact dermatitis after using Dermatop cream and -ointment for several weeks. Patch tests were positive with the reagent prednicarbate itself. No cross reactions to other glucocorticosteroids were observed. Type-IV-sensitization to glucocorticosteroids should be considered if chronic dermatitis does not improve, or even becomes worse, in spite of adequate therapy. With regard to possible cross reactions or multiple sensitization, epicutaneous tests with other glucocorticosteroids are necessary.
两名女性患者在使用德美罗乳膏和软膏数周后出现过敏性接触性皮炎。斑贴试验显示,试剂泼尼松龙自身呈阳性。未观察到与其他糖皮质激素的交叉反应。如果慢性皮炎在充分治疗后仍未改善甚至加重,则应考虑对糖皮质激素的IV型致敏。考虑到可能的交叉反应或多重致敏,有必要对其他糖皮质激素进行皮肤试验。