Krayer Joe W, Leite Renata S, Kirkwood Keith L
Department of Stomatology, College of Dental Medicine, Medical University of South Carolina, 30 Bee Steet - room 115, Charleston, SC 29425, USA.
Dent Clin North Am. 2010 Jan;54(1):13-33. doi: 10.1016/j.cden.2009.08.010.
Periodontal diseases are initiated by subgingival periodontal pathogens in susceptible periodontal sites. The host immune response toward periodontal pathogens helps to sustain periodontal disease and eventual alveolar bone loss. Numerous adjunctive therapeutic strategies have evolved to manage periodontal diseases. Systemic and local antibiotics, antiseptics, and past and future host immune modulatory agents are reviewed and discussed to facilitate the dental practitioner's appreciation of this ever-growing field in clinical periodontics.
牙周疾病由易感牙周部位的龈下牙周病原体引发。宿主对牙周病原体的免疫反应有助于维持牙周疾病并最终导致牙槽骨丧失。已发展出多种辅助治疗策略来管理牙周疾病。本文对全身及局部使用的抗生素、防腐剂以及过去和未来的宿主免疫调节剂进行综述和讨论,以促进牙科医生对临床牙周病学这一不断发展领域的了解。