Department of Thoracic Surgery, Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, Canada.
J Cardiovasc Med (Hagerstown). 2013 Apr;14(4):314-6. doi: 10.2459/JCM.0b013e3283340b5d.
Platypnea-orthodeoxia syndrome is a rare and poorly understood condition related to the development of a right-to-left intracardiac shunt at the atrial level through a benign and silent patent foramen ovale. It is usually recognized after major lung resection, recurrent pulmonary embolism or chronic lung disease. Orthostatic dyspnea and cyanosis is the prominent clinical presentation. Symptoms increase in the upright position and are relieved by recumbency. Our report describes the clinical course of a patient with severe hypoxemia after left pneumonectomy attributable to a right-to-left shunting through an atrial septal defect.
并发性直立性低氧血症-低通气综合征是一种罕见且尚未完全阐明的病症，与卵圆孔未闭导致的右向左心内分流有关，而卵圆孔未闭通常是良性且无症状的。它通常发生在大肺切除术后、复发性肺栓塞或慢性肺部疾病后。直立性呼吸困难和发绀是突出的临床表现。症状在直立位时加重，卧位时缓解。我们的报告描述了一例左侧肺切除术后严重低氧血症患者的临床过程，该患者归因于通过房间隔缺损的右向左分流。
