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Optimal response to thalidomide in a patient with thalassaemia major resistant to conventional therapy.

作者信息

Masera Nicoletta, Tavecchia Luisa, Capra Marietta, Cazzaniga Giovanni, Vimercati Chiara, Pozzi Lorena, Biondi Andrea, Masera Giuseppe

机构信息

Clinica Pediatrica, Università di Milano-Bicocca, Ospedale San Gerardo, Monza, Italy.

出版信息

Blood Transfus. 2010 Jan;8(1):63-5. doi: 10.2450/2009.0102-09.

DOI:10.2450/2009.0102-09
PMID:20104280
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2809513/
Abstract
摘要

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本文引用的文献

1
Haemoglobin F modulation in childhood sickle cell disease.儿童镰状细胞病中的胎儿血红蛋白调节
Br J Haematol. 2009 Feb;144(3):308-16. doi: 10.1111/j.1365-2141.2008.07482.x. Epub 2008 Nov 20.
2
Thalidomide therapy in a patient with thalassemia major.一名重型地中海贫血患者的沙利度胺治疗。
Blood Cells Mol Dis. 2008 Jul-Aug;41(1):136-7. doi: 10.1016/j.bcmd.2008.03.001. Epub 2008 Apr 24.
3
Pomalidomide and lenalidomide regulate erythropoiesis and fetal hemoglobin production in human CD34+ cells.泊马度胺和来那度胺调节人CD34+细胞中的红细胞生成和胎儿血红蛋白生成。
J Clin Invest. 2008 Jan;118(1):248-58. doi: 10.1172/JCI32322.
4
Thalidomide induces gamma-globin gene expression through increased reactive oxygen species-mediated p38 MAPK signaling and histone H4 acetylation in adult erythropoiesis.沙利度胺通过增加活性氧介导的p38丝裂原活化蛋白激酶信号传导和组蛋白H4乙酰化，在成人红细胞生成中诱导γ-珠蛋白基因表达。
Blood. 2007 Oct 15;110(8):2864-71. doi: 10.1182/blood-2007-01-065201. Epub 2007 Jul 9.
5
Maintenance of elevated fetal hemoglobin levels by decitabine during dose interval treatment of sickle cell anemia.地西他滨在镰状细胞贫血间歇给药治疗期间维持胎儿血红蛋白水平升高
Blood. 2002 Jun 1;99(11):3905-8. doi: 10.1182/blood.v99.11.3905.
6
Hydroxyurea increases hemoglobin F levels and improves the effectiveness of erythropoiesis in beta-thalassemia/hemoglobin E disease.羟基脲可提高血红蛋白F水平，并改善β地中海贫血/血红蛋白E病中红细胞生成的有效性。
Blood. 1996 Feb 1;87(3):887-92.
7
Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia.羟基脲对镰状细胞贫血疼痛性危象发作频率的影响。镰状细胞贫血羟基脲多中心研究的研究者们。
N Engl J Med. 1995 May 18;332(20):1317-22. doi: 10.1056/NEJM199505183322001.
8
Pharmacologic treatment of thalassemia intermedia with hydroxyurea.用羟基脲对中间型地中海贫血进行药物治疗。
J Pediatr. 1994 Sep;125(3):490-2. doi: 10.1016/s0022-3476(05)83304-9.
9
Hydroxyurea enhances fetal hemoglobin production in sickle cell anemia.羟基脲可提高镰状细胞贫血患者的胎儿血红蛋白生成水平。
J Clin Invest. 1984 Aug;74(2):652-6. doi: 10.1172/JCI111464.
10
5-azacytidine selectively increases gamma-globin synthesis in a patient with beta+ thalassemia.5-氮杂胞苷可选择性增加一名β+地中海贫血患者的γ珠蛋白合成。
N Engl J Med. 1982 Dec 9;307(24):1469-75. doi: 10.1056/NEJM198212093072401.