[对因急性肠胃炎住院儿童的人细小病毒检测]
[Detection of human parechovirus in children hospitalized for acute gastroenteritis].
作者信息
Zhang Dong-liang, Zhang Qing, Li Dan-di, Cheng Wei-xia, Xu Zi-qian, Jin Miao, Yu Jie-mei, Zhu Lin, Cui Shu-xian, Li Pei-zhen, Duan Zhao-jun
机构信息
College of Public Health, Shanxi Medical University, Taiyuan 030001, China.
出版信息
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2009 Apr;23(2):112-4.
OBJECTIVE
To detect human parechovirus (HPeV) from stool samples of hospitalized children for acute gastroenteritis of undetectable etiology.
METHODS
We conducted a real-time PCR to detect HPeV.
RESULT
The results showed that 24 of 99 (24%) children with gastroenteritis of undetectable etiology were detected with HPeV. Four known HPeV types (HPeV1, 3, 4, 6) were detected in the present study. HPeV1 (50%) was frequently identified as the predominant strain and follow by HPeV3 (25%), HPeV4 (8.3%) and HPeV6 (4.2%). We were unable to type 3 samples.
CONCLUSION
HPeV was prevalent in hospitalized children for acute gastroenteritis of undetectable etiology in China. Further study is needed for clarifying the role of HPeV in gastroenteritis.
目的
从病因不明的急性胃肠炎住院儿童粪便样本中检测人细小病毒（HPeV）。
方法
我们进行了实时聚合酶链反应（PCR）以检测HPeV。
结果
结果显示，99例病因不明的胃肠炎儿童中有24例（24%）检测出HPeV。本研究检测到4种已知的HPeV型别（HPeV1、3、4、6）。HPeV1（50%）是最常鉴定出的优势毒株，其次是HPeV3（25%）、HPeV4（8.3%）和HPeV6（4.2%）。有3份样本无法分型。
结论
HPeV在中国病因不明的急性胃肠炎住院儿童中很常见。需要进一步研究以阐明HPeV在胃肠炎中的作用。
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