Department of Urology, Endourology and Stone Services, Barts and The London National Health Service Trust, London, United Kingdom.
J Endourol. 2010 Mar;24(3):487-91. doi: 10.1089/end.2009.0138.
We assess the safety, efficacy, and cost of the novel long-term indwelling thermo-expandable Memokath ureteral stent for the management of malignant and benign ureteral strictures.
Since October 2004, we treated 73 patients (34 men), ages 23 to 84 years (mean 57.7) with 86 ureteral strictures (13 bilateral) with the Memokath 051 stent. The causes of the strictures were benign in 55 cases and malignant in 31 cases. Follow-up included radiography, renal ultrasonography, and renography if needed after 2 weeks, 3 months, and then every 6 months.
The mean operative time was 23 minutes, while the mean hospital stay was 1.5 days. The average indwelling time of an individual Memokath was 11.2 months. After a mean follow-up period of 17.1 months, there were 68 stents in situ. In 12 cases, spontaneous resolution of the ureteral stricture was revealed after a mean indwelling time of 9 months. The remainding six cases were treatment failures. In 15 cases, because of late complications, a Memokath exchange took place after a mean period of 18 months. A total of 26 complications were revealed after the insertion of 102 Memokath stents. These included six cases of urinary tract infections; 15 stent manipulations were needed because of stent dislodgement, and 5 stents were removed because of encrustration and blockage. In the long term, the overall costs for the Memokath treatment and follow-up were considerably less than with the conventional Double-J stent.
The ureteral Memokath stent is a promising, safe, and efficient treatment option for the minimally invasive management of both benign and malignant ureteral strictures.
我们评估新型长期留置热膨胀 Memokath 输尿管支架在治疗恶性和良性输尿管狭窄中的安全性、疗效和成本。
自 2004 年 10 月以来,我们用 Memokath 051 支架治疗了 73 例(34 名男性)年龄 23 至 84 岁(平均 57.7 岁)的 86 例输尿管狭窄(13 例双侧)。狭窄的原因在 55 例为良性,31 例为恶性。随访包括放射学、肾脏超声检查和必要时的肾图检查,分别在 2 周、3 个月后进行,然后每 6 个月进行一次。
平均手术时间为 23 分钟,平均住院时间为 1.5 天。单个 Memokath 的平均留置时间为 11.2 个月。在平均 17.1 个月的随访后,有 68 个支架仍在原位。在 12 例中,在平均 9 个月的留置时间后发现输尿管狭窄自发缓解。其余 6 例治疗失败。在 15 例中,由于晚期并发症,在平均 18 个月后进行了 Memokath 交换。在插入 102 个 Memokath 支架后,共发现 26 种并发症。其中包括 6 例尿路感染;由于支架移位,需要进行 15 次支架操作;由于包埋和阻塞,有 5 个支架被取出。从长远来看,Memokath 治疗和随访的总成本明显低于传统的双 J 支架。
输尿管 Memokath 支架是一种有前途、安全且有效的治疗选择,可用于微创治疗良性和恶性输尿管狭窄。