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长期支架治疗输尿管狭窄的系统评价:该如何选择?

A systematic review of long-duration stents for ureteral stricture: which one to choose?

机构信息

GRC Urolithiasis no. 20, Tenon Hospital, Sorbonne University, 75020, Paris, France.

Department of Urology AP-HP, Tenon Hospital, Sorbonne University, 75020, Paris, France.

出版信息

World J Urol. 2021 Sep;39(9):3197-3205. doi: 10.1007/s00345-020-03544-x. Epub 2021 Jan 2.

Abstract

OBJECTIVE

To define which long-term stent would work best in malignant ureteral obstruction (MUO) and benign ureteral obstruction (BUO), focusing on their mechanisms of action, price and insertion approach.

METHODS

A systematic review was developed using the MEDLINE and Scopus databases and in accordance with the PRISMA checklist. There were no language restrictions for the search. Studies describing the use of metallic ureteric stents for MUO and for BUO in humans were included.

RESULTS

We analyzed five types of metallic stents (35 papers) and also the experience with the tumor and extra-anatomical stents. The Resonance, Memokath and Allium ureteral stents were found to be useful in BUO and MUO. The Uventa stent performed well in chronic ureteral obstruction. The Detour bypass stent was a recommended option in those patients who had complete obstruction of the ureter and were unfit for reconstructive surgery. There was no difference with regard to the insertion technique and both antegrade and retrograde approaches were equally successful. Although tumor stents showed a good performance, there were very few published studies on it.

CONCLUSION

Metallic stents are a suitable option for MUO and BUO. When compared to standard double J stents, although they are relatively high priced, they show a financial benefit in the long-term. The Detour bypass stent seems to be an effective alternative for complete ureteral obstruction or patients unfit for surgery. Further prospective randomized studies should be done on the effectiveness of tumor stents versus metallic stents.

摘要

目的

确定哪种长期支架最适合恶性输尿管梗阻 (MUO) 和良性输尿管梗阻 (BUO),重点关注它们的作用机制、价格和插入方法。

方法

使用 MEDLINE 和 Scopus 数据库开发了系统评价,并符合 PRISMA 清单的要求。搜索没有语言限制。纳入描述用于 MUO 和 BUO 的金属输尿管支架的人类研究。

结果

我们分析了 5 种类型的金属支架(35 篇论文),以及肿瘤和解剖外支架的经验。Resonance、Memokath 和 Allium 输尿管支架被发现对 BUO 和 MUO 有用。Uventa 支架在慢性输尿管梗阻中表现良好。Detour 旁路支架是那些完全梗阻输尿管且不适合重建手术的患者的推荐选择。插入技术没有差异,顺行和逆行方法同样成功。虽然肿瘤支架表现良好,但发表的研究很少。

结论

金属支架是 MUO 和 BUO 的合适选择。与标准的双 J 支架相比,虽然价格相对较高,但它们在长期内具有经济优势。Detour 旁路支架似乎是完全输尿管梗阻或不适合手术的患者的有效替代方案。应进一步进行关于肿瘤支架与金属支架有效性的前瞻性随机研究。

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