Ong Lai Choo, Yang Wai Wai, Wong Sau Wei, alSiddiq Feizel, Khu Yi Soon
Department of Paediatrics, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Kuala Lumpur, Malaysia.
J Paediatr Child Health. 2010 Mar;46(3):80-4. doi: 10.1111/j.1440-1754.2009.01642.x. Epub 2010 Jan 26.
To compare sleep habits and disturbances between Malaysian children with epilepsy and their siblings (age range 4-18 years) and to determine the factors associated with greater sleep disturbance.
The Sleep Disturbance Scale for Children (SDSC) questionnaire was completed by the primary caregiver for 92 epileptic children (mean age 11.1 years, 50 male, 42 females) and their healthy siblings (mean age 11.1 years, 47 males, 45 females). Details of sleep arrangements and illness severity were obtained. Multiple regression analysis was used to determine factors associated with high Total SDSC scores in epileptic patients.
Compared with their siblings, epileptic children had significantly higher total SDSC score (difference between means 8.7, 95% confidence interval (CI) 6.4-11.1) and subscale scores in disorders of initiating and maintaining sleep (3.9, 95% CI 2.8-5.2), sleep-wake transition disorders (2.1, 95% CI 1.3-2.9), sleep-disordered breathing (0.7, 95% CI 0.3-1.1) and disorders of excessive sleepiness (1.5, 95% CI 0.6-2.4). Epileptic children had a higher prevalence of co-sleeping (73.7% vs 31.5%) and on more nights per week (difference between means 3, 95% CI 2.0-3.9) than their siblings. Higher Epilepsy Illness Severity scores were associated with higher total SDSC scores (P= 0.02).
Co-sleeping was highly prevalent in children with epilepsy, who also had more sleep disturbances (especially problems with initiating and maintaining sleep and sleep-wake transition disorders) than their siblings. Epilepsy severity contributed to the sleep disturbances. Evaluation of sleep problems should form part of the comprehensive care of children with severe epilepsy.
比较马来西亚癫痫患儿与其兄弟姐妹（年龄范围4至18岁）的睡眠习惯及睡眠障碍情况，并确定与更严重睡眠障碍相关的因素。
由主要照顾者为92名癫痫患儿（平均年龄11.1岁，50名男性，42名女性）及其健康的兄弟姐妹（平均年龄11.1岁，47名男性，45名女性）完成儿童睡眠障碍量表（SDSC）问卷。获取睡眠安排及疾病严重程度的详细信息。采用多元回归分析确定癫痫患者SDSC总分高的相关因素。
与他们的兄弟姐妹相比，癫痫患儿的SDSC总分显著更高（均值差异为8.7，95%置信区间（CI）6.4 - 11.1），在入睡和维持睡眠障碍（3.9，95%CI 2.8 - 5.2）、睡眠 - 觉醒转换障碍（2.1，95%CI 1.3 - 2.9）、睡眠呼吸障碍（0.7，95%CI 0.3 - 1.1）及过度嗜睡障碍（1.5，95%CI 0.6 - 2.4）方面的分量表得分也更高。癫痫患儿同睡的患病率（73.7%对31.5%）更高，且每周同睡的夜晚更多（均值差异为3，95%CI 2.0 - 3.9）。癫痫疾病严重程度得分越高，SDSC总分越高（P = 0.02）。
同睡在癫痫患儿中非常普遍，他们比兄弟姐妹有更多的睡眠障碍（尤其是入睡和维持睡眠问题以及睡眠 - 觉醒转换障碍）。癫痫严重程度导致了睡眠障碍。睡眠问题的评估应成为重度癫痫患儿综合护理的一部分。
