Dykman R A, Ackerman P T
University of Arkansas for Medical Sciences.
J Learn Disabil. 1991 Feb;24(2):96-103. doi: 10.1177/002221949102400206.
Within a large (N = 182) heterogeneous sample of clinic-referred children with DSM-III-diagnosed attention deficit disorder (ADD), three behavioral subgroups were identified via cluster analysis of teacher ratings: 40% of the children had ADD with hyperactivity (ADDH), 30% had ADD with hyperactivity and aggressivity (ADDHA), and 31% had ADD without hyperactivity or aggressivity. Proportionally more girls were in the ADD-only subgroup. Over half the sample (n = 94) were poor readers, with 82 meeting discrepancy criteria for specific reading disability (RD). Proportionately more boys than girls met the RD criteria (9.2:1.0), whereas the sex ratio of males to females for the whole sample was 5.1 to 1.0. Focusing just on white males, the three behavioral subgroups were significantly different on convergent validity measures, such as other teacher ratings, parent ratings, and interview-elicited ratings of externalizing behavior, but were not different on such divergent validity measures as IQ and achievement scores, self-ratings, and laboratory performance tasks. Boys in the ADD sample who did not meet criteria for RD had significantly higher IQs than those who did, but subgroups with and without RD still differed significantly on WRAT-R reading and spelling scores with IQ covaried out. Both groups with and without RD could be differentiated from a control group on laboratory measures of sustained attention and impulse control. Methylphenidate benefited all subgroups equally, whether RD or not, and whether given a low (0.3 mg/kg) or high (0.6 mg/kg) dose.
在一个规模较大(N = 182)、由临床转介的患有DSM-III诊断的注意力缺陷障碍(ADD)的儿童组成的异质样本中,通过对教师评分进行聚类分析,确定了三个行为亚组:40%的儿童患有多动型注意力缺陷障碍(ADDH),30%的儿童患有多动攻击型注意力缺陷障碍(ADDHA),31%的儿童患有无多动或攻击行为的注意力缺陷障碍。仅患ADD亚组中的女孩比例相对较高。超过一半的样本(n = 94)阅读能力较差,其中82人符合特定阅读障碍(RD)的差异标准。达到RD标准的男孩与女孩的比例相对较高(9.2:1.0),而整个样本中男性与女性的性别比为5.1:1.0。仅关注白人男性,这三个行为亚组在收敛效度指标上存在显著差异,如其他教师评分、家长评分以及访谈得出的外化行为评分,但在诸如智商和成就分数、自我评分以及实验室表现任务等区分效度指标上并无差异。ADD样本中未达到RD标准的男孩的智商显著高于达到标准的男孩,但在控制智商因素后,有RD和无RD的亚组在WRAT-R阅读和拼写分数上仍存在显著差异。有RD和无RD的两组在持续注意力和冲动控制的实验室测量指标上均能与对照组区分开来。哌甲酯对所有亚组的效果相同,无论是否患有RD,也无论给予低剂量(0.3 mg/kg)还是高剂量(0.6 mg/kg)。