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使用 SwissVar 轻松检索单氨基酸多态性和表型信息。

Easy retrieval of single amino-acid polymorphisms and phenotype information using SwissVar.

机构信息

Swiss Institute of Bioinformatics , Centre Médical Universitaire, 1211 Geneva 4, Switzerland.

出版信息

Bioinformatics. 2010 Mar 15;26(6):851-2. doi: 10.1093/bioinformatics/btq028. Epub 2010 Jan 26.

DOI:10.1093/bioinformatics/btq028
PMID:20106818
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2832822/
Abstract

SUMMARY

The SwissVar portal provides access to a comprehensive collection of single amino acid polymorphisms and diseases in the UniProtKB/Swiss-Prot database via a unique search engine. In particular, it gives direct access to the newly improved Swiss-Prot variant pages. The key strength of this portal is that it provides a possibility to query for similar diseases, as well as the underlying protein products and the molecular details of each variant. In the context of the recently proposed molecular view on diseases, the SwissVar portal should be in a unique position to provide valuable information for researchers and to advance research in this area.

AVAILABILITY

The SwissVar portal is available at www.expasy.org/swissvar

CONTACT

anais.mottaz@isb-sib.ch; lina.yip@isb-sib.ch

SUPPLEMENTARY INFORMATION

Supplementary data are available at Bioinformatics online.

摘要

摘要

SwissVar 门户通过一个独特的搜索引擎提供了对 UniProtKB/Swiss-Prot 数据库中全面的单氨基酸多态性和疾病的访问。特别是，它可以直接访问新改进的 Swiss-Prot 变体页面。该门户的主要优势在于，它提供了查询类似疾病以及潜在的蛋白质产物和每个变体的分子细节的可能性。在最近提出的疾病分子观点的背景下，SwissVar 门户应该能够为研究人员提供有价值的信息，并推动该领域的研究。

可用性

SwissVar 门户可在 www.expasy.org/swissvar 获得

联系人

an ais.mottaz@isb-sib.ch；lina.yip@isb-sib.ch

补充信息

补充数据可在 Bioinformatics 在线获得。

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