University Program in Genetics and Genomics, Duke University Medical Center, Durham, NC 27710, USA.
Biol Lett. 2010 Aug 23;6(4):502-4. doi: 10.1098/rsbl.2009.0969. Epub 2010 Jan 27.
Tremendous advances in genetic and genomic techniques have resulted in the capacity to identify genes involved in adaptive evolution across numerous biological systems. One of the next major steps in evolutionary biology will be to determine how landscape-level geographical and environmental features are involved in the distribution of this functional adaptive genetic variation. Here, I outline how an emerging synthesis of multiple disciplines has and will continue to facilitate a deeper understanding of the ways in which heterogeneity of the natural landscapes mould the genomes of organisms.
遗传和基因组技术的巨大进步使得我们有能力识别众多生物系统中与适应性进化相关的基因。进化生物学的下一个主要步骤之一将是确定景观水平的地理和环境特征如何参与这种功能适应性遗传变异的分布。在这里,我概述了多个学科的新兴综合如何并将继续促进我们更深入地理解自然景观的异质性塑造生物体基因组的方式。