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从急诊科出院的心衰患者的早期死亡:一项基于人群的分析。

Early deaths in patients with heart failure discharged from the emergency department: a population-based analysis.

机构信息

Division of Cardiology, Institute for Clinical Evaluative Sciences, Toronto General Hospital, Toronto, Ontario, Canada.

出版信息

Circ Heart Fail. 2010 Mar;3(2):228-35. doi: 10.1161/CIRCHEARTFAILURE.109.885285. Epub 2010 Jan 27.

Abstract

BACKGROUND

Although approximately one third of patients with heart failure (HF) visiting the emergency department (ED) are discharged home, little is known about their care and outcomes.

METHODS AND RESULTS

We examined the acute care and early outcomes of patients with HF who visited an ED and were discharged without hospital admission in Ontario, Canada, from April 2004 to March 2007. Among 50 816 patients (age, 76.4+/-11.6 years; 49.4% men) visiting an ED for HF, 16 094 (31.7%) were discharged without hospital admission. A total of 4.0% died within 30 days from admission, and 1.3% died within 7 days of discharge from the ED. Although multiple (>or=2) previous HF admissions (odds ratio [OR], 1.64; 95% CI, 1.14 to 2.31), valvular heart disease (OR, 1.37; 95% CI, 1.00 to 1.84), peripheral vascular disease (OR, 1.41; 95% CI, 1.00 to 1.93), and respiratory disease (OR, 1.33; 95% CI, 1.08 to 1.63) increased the risk of 30-day death among those discharged from the ED, presence of these conditions did not increase the likelihood of admission. Patients were more likely to be admitted if they were older (OR, 1.08; 95% CI, 1.06 to 1.10 per decade), arrived by ambulance (OR, 2.02; 95% CI, 1.93 to 2.12), had a higher triage acuity score (OR, 4.12; 95% CI, 3.84 to 4.42), or received resuscitation in the ED (OR, 2.85; 95% CI, 2.68 to 3.04). In those with comparable predicted risks of death, subsequent 90-day mortality rates were higher among discharged than admitted patients (11.9% versus 9.5%; log-rank P=0.016).

CONCLUSIONS

Patients with HF who are discharged from the ED have substantial risks of early death, which, in some cases, may exceed that of hospitalized patients.

摘要

背景

尽管约有三分之一因心力衰竭(HF)就诊于急诊部(ED)的患者被出院回家,但对他们的护理和结局知之甚少。

方法和结果

我们研究了 2004 年 4 月至 2007 年 3 月期间,加拿大安大略省因 HF 就诊 ED 且未入院的患者的急性护理和早期结局。在因 HF 就诊 ED 且未入院的 50816 名患者(年龄 76.4+/-11.6 岁;49.4%为男性)中,有 16094 名(31.7%)被出院。入院后 30 天内有 4.0%的患者死亡,出院后 7 天内有 1.3%的患者死亡。尽管有多次(>或=2 次)HF 入院(比值比 [OR],1.64;95%置信区间,1.14 至 2.31)、瓣膜性心脏病(OR,1.37;95%置信区间,1.00 至 1.84)、外周血管疾病(OR,1.41;95%置信区间,1.00 至 1.93)和呼吸系统疾病(OR,1.33;95%置信区间,1.08 至 1.63)增加了 ED 出院患者 30 天内死亡的风险,但这些情况并没有增加入院的可能性。如果患者年龄较大(OR,1.08;95%置信区间,每十年增加 1.06 至 1.10)、通过救护车抵达(OR,2.02;95%置信区间,1.93 至 2.12)、分诊 acuity 评分较高(OR,4.12;95%置信区间,3.84 至 4.42)或在 ED 接受复苏(OR,2.85;95%置信区间,2.68 至 3.04),则更有可能入院。在具有可比死亡风险预测的患者中,出院患者的 90 天死亡率高于入院患者(11.9%比 9.5%;对数秩 P=0.016)。

结论

从 ED 出院的 HF 患者有早期死亡的巨大风险,在某些情况下,死亡风险可能超过住院患者。

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