Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371.
Chem Commun (Camb). 2010 Feb 14;46(6):922-4. doi: 10.1039/b918588g. Epub 2009 Dec 4.
The direct synthesis of amides by insertion into the C-H bond of aldehydes is shown to be a practical procedure through application of cheap, readily available catalysts generated in situ from copper(i) halides and pyridine.
通过应用廉价、易得的铜(I)卤化物和吡啶原位生成的催化剂,将酰胺直接插入醛的 C-H 键中被证明是一种实用的方法。