Kessels A G, Cardynaals R L, Borger R L, Go M J, Lambers J C, Knottnerus J A, Knipschild P G
Department of Epidemiology/Health Care Research, University of Limburg, Maastricht, The Netherlands.
J Clin Epidemiol. 1991;44(4-5):439-47. doi: 10.1016/0895-4356(91)90083-l.
In a randomized, double-blind trial the effectiveness of 6 months' use of a Chinese herb extract (Dabao) as a hair-restorer was studied on 396 males with alopecia androgenetica. The effect was evaluated by nonvellus hair counts, participants' opinions and a panel's judgement of a photo-report. Twenty-three participants withdrew prematurely from the study. In both the Dabao and placebo groups an increase in the amount of hair was observed; 133 and 109 hairs on a 5 cm2 marked area, a difference of 24 hairs (p = 0.03, one-sided). Participants as well as the panel reached a similar conclusion. Regarding cosmetic effect, 42% of the participants in the Dabao group and 37% in the placebo group reported positive results. The average panel score for the cosmetic result on a scale of -10 to +10 was 0.46 in the Dabao and 0.21 in the placebo group, a difference of 0.24 (p = 0.04, one-sided). It appears from our study that, although the cosmetic effect over 6 months is modest, Dabao does have a certain effect on the growth of nonvellus hair.
在一项随机双盲试验中，对396名雄激素性脱发男性研究了使用一种中草药提取物（大宝）6个月作为生发剂的有效性。通过非毳毛计数、参与者的意见以及专家组对照片报告的评判来评估效果。23名参与者提前退出了研究。在大宝组和安慰剂组中均观察到毛发数量增加；在5平方厘米的标记区域分别增加了133根和109根毛发，相差24根（p = 0.03，单侧）。参与者和专家组得出了类似的结论。关于美容效果，大宝组42%的参与者和安慰剂组37%的参与者报告了积极结果。在-10至+10的量表上，大宝组美容效果的专家组平均评分为0.46，安慰剂组为0.21，相差0.24（p = 0.04，单侧）。从我们的研究来看，虽然6个月的美容效果不显著，但大宝对非毳毛的生长确实有一定作用。
