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[急性病毒性和新发病毒性中枢神经系统感染]

[Acute viral and emerging viral CNS infections].

作者信息

Menon S, Lenhard T, Meyding-Lamadé U

机构信息

Neurologische Klinik, Krankenhaus Nordwest GmbH, Steinbacher Hohl 2-26, Frankfurt am Main, Germany.

出版信息

Nervenarzt. 2010 Feb;81(2):138-49. doi: 10.1007/s00115-009-2855-5.

Abstract

The morbidity and mortality of viral CNS infections can be reduced through early initiation of therapy, which could be specific or in most cases symptomatic. This in turn requires the physician to consider meningoencephalitis as a differential diagnosis.Increasing climate changes, global air travel and changing immune responses contribute to the emergence of rather rare viral pathogens on our continent. Thus, neurologists in Europe are facing an enormous challenge due to lacking knowledge and experience of these new germs, which needs to be taken care of.Novel therapeutic approaches with e.g. monoclonal antibodies awaken the hope of mitigating the partially lethal courses of these diseases.

摘要

通过早期开始治疗可以降低病毒性中枢神经系统感染的发病率和死亡率,治疗可以是特异性的,在大多数情况下是对症治疗。这反过来要求医生将脑膜脑炎作为鉴别诊断。气候变化加剧、全球航空旅行以及免疫反应的变化促使我们大陆出现了相当罕见的病毒病原体。因此,由于对这些新病菌缺乏了解和经验,欧洲的神经科医生面临着巨大挑战,这一情况需要得到关注。例如单克隆抗体等新型治疗方法带来了减轻这些疾病部分致死病程的希望。

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