Huffman J E, Sabol C, Fried B
Department of Biological Sciences, East Stroudsburg University, Pennsylvania 18301.
J Parasitol. 1991 Apr;77(2):280-4.
Laboratory mice, rats, and golden hamsters were fed metacercarial cysts of Zygocotyle lunata to examine infectivity, growth, survival, and pathogenicity of this trematode. All 3 rodent types became infected with Z. lunata. Eggs of Z. lunata were seen in the feces of the hamsters by day 21, in mice by day 26, and in rats by day 44. Eggs teased from worms and embryonated in tap water hatched from day 21 to day 26 for rats and mice and from day 40 to day 45 for hamsters. The body areas of sexually mature worms were similar in all 3 types of rodent species. It was possible to reinfect all 3 species with Z. lunata metacercariae. No sign of clinical amphistomiasis was evident in the experimental animals. The histopathological responses were progressive, and severity was related to the age of the infection and the number of worms in the infection.
给实验小鼠、大鼠和金黄仓鼠喂食月形合盘吸虫的后尾蚴囊肿，以检查这种吸虫的感染性、生长、存活情况和致病性。所有这三种啮齿动物都感染了月形合盘吸虫。在第21天在仓鼠粪便中发现了月形合盘吸虫的卵，在第26天在小鼠粪便中发现，在第44天在大鼠粪便中发现。从虫体中取出的卵在自来水中孵化，大鼠和小鼠在第21天至第26天孵化，仓鼠在第40天至第45天孵化。在所有三种啮齿动物物种中，性成熟虫体的身体部位相似。用月形合盘吸虫的后尾蚴再次感染所有这三个物种是可能的。在实验动物中没有明显的临床双口吸虫病迹象。组织病理学反应是渐进性的，严重程度与感染年龄和感染中的虫体数量有关。
