Sherman A I, Reid R
Sinai Hospital of Detroit, Wayne State University School of Medicine, MI.
J Reprod Med. 1991 Feb;36(2):113-7.
Chronic suppurative hidradenitis is a disease of the apocrine glands occurring predominantly in the axillae of the anogenital region. Treatment, to date, has been frustrating. Prolonged antibiotic therapy and multiple incisions and drainage have been the usual form of therapy, but those surgical procedures leave patients with ugly scars; retracted, hypertrophic skin edges; and pitted, indurated and disfiguring abscesses. The only successful treatment to date has been wide excision of the entire apocrine gland-bearing tissues, such as radical vulvectomy, which often necessitates grafts to cover the surgically exposed areas. That has left patients with unsatisfactorily functioning vaginas and a mutilated appearance. Recently we instituted the use of the CO2 laser to treat these patients with the goal of eradicating the suppurative sinus tracts and the infected apocrine glands without removing large volumes of adjacent, unaffected tissue. Over the past eight years we treated 11 patients who had extensive, chronic hidradenitis of the anogenital area with the CO2 laser. The use of laser therapy for these patients has produced effective and less-mutilating results. Such treatment has been a successful option for treating this debilitating disease.
慢性化脓性汗腺炎是一种主要发生于肛周和生殖器区域腋窝处的顶泌汗腺疾病。迄今为止,其治疗一直令人沮丧。长期抗生素治疗以及多次切开引流一直是常用的治疗方式,但这些外科手术会给患者留下难看的疤痕、回缩且肥厚的皮肤边缘以及凹陷、硬结且毁容的脓肿。迄今为止唯一成功的治疗方法是广泛切除整个含有顶泌汗腺的组织,比如根治性外阴切除术,这通常需要移植皮瓣来覆盖手术暴露区域。这使得患者阴道功能不尽人意且外观残缺。最近我们开始使用二氧化碳激光来治疗这些患者,目标是根除化脓性窦道和受感染的顶泌汗腺,而无需切除大量相邻的未受影响组织。在过去八年里,我们用二氧化碳激光治疗了11例患有广泛慢性肛周和生殖器区域汗腺炎的患者。对这些患者使用激光治疗已产生了有效且创伤较小的效果。这种治疗方法是治疗这种使人衰弱疾病的一种成功选择。