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二氧化碳激光治疗外阴化脓性汗腺炎

CO2 laser for suppurative hidradenitis of the vulva.

作者信息

Sherman A I, Reid R

机构信息

Sinai Hospital of Detroit, Wayne State University School of Medicine, MI.

出版信息

J Reprod Med. 1991 Feb;36(2):113-7.

PMID:2010892
Abstract

Chronic suppurative hidradenitis is a disease of the apocrine glands occurring predominantly in the axillae of the anogenital region. Treatment, to date, has been frustrating. Prolonged antibiotic therapy and multiple incisions and drainage have been the usual form of therapy, but those surgical procedures leave patients with ugly scars; retracted, hypertrophic skin edges; and pitted, indurated and disfiguring abscesses. The only successful treatment to date has been wide excision of the entire apocrine gland-bearing tissues, such as radical vulvectomy, which often necessitates grafts to cover the surgically exposed areas. That has left patients with unsatisfactorily functioning vaginas and a mutilated appearance. Recently we instituted the use of the CO2 laser to treat these patients with the goal of eradicating the suppurative sinus tracts and the infected apocrine glands without removing large volumes of adjacent, unaffected tissue. Over the past eight years we treated 11 patients who had extensive, chronic hidradenitis of the anogenital area with the CO2 laser. The use of laser therapy for these patients has produced effective and less-mutilating results. Such treatment has been a successful option for treating this debilitating disease.

摘要

慢性化脓性汗腺炎是一种主要发生于肛周和生殖器区域腋窝处的顶泌汗腺疾病。迄今为止,其治疗一直令人沮丧。长期抗生素治疗以及多次切开引流一直是常用的治疗方式,但这些外科手术会给患者留下难看的疤痕、回缩且肥厚的皮肤边缘以及凹陷、硬结且毁容的脓肿。迄今为止唯一成功的治疗方法是广泛切除整个含有顶泌汗腺的组织,比如根治性外阴切除术,这通常需要移植皮瓣来覆盖手术暴露区域。这使得患者阴道功能不尽人意且外观残缺。最近我们开始使用二氧化碳激光来治疗这些患者,目标是根除化脓性窦道和受感染的顶泌汗腺,而无需切除大量相邻的未受影响组织。在过去八年里,我们用二氧化碳激光治疗了11例患有广泛慢性肛周和生殖器区域汗腺炎的患者。对这些患者使用激光治疗已产生了有效且创伤较小的效果。这种治疗方法是治疗这种使人衰弱疾病的一种成功选择。

相似文献

1
CO2 laser for suppurative hidradenitis of the vulva.二氧化碳激光治疗外阴化脓性汗腺炎
J Reprod Med. 1991 Feb;36(2):113-7.
2
Advanced hidradenitis suppurativa of the vulva. A report of three cases.
J Reprod Med. 1984 Jul;29(7):436-40.
3
[Suppurative hidradenitis].[化脓性汗腺炎]
Ned Tijdschr Geneeskd. 1997 Jul 26;141(30):1484-7.
4
[Surgical treatment of a disseminated form of chronic suppurative hidradenitis].[慢性化脓性汗腺炎播散型的外科治疗]
Vestn Khir Im I I Grek. 1980 Jan;124(1):78-82.
5
[Chronic suppurative hidradenitis axillaris].[慢性化脓性腋窝汗腺炎]
Z Hautkr. 1979 Oct 15;54(20):936-40.
6
[Surgical treatment of suppurative axillary hidradenitis: value of a musculocutaneous island flap of the latissimus dorsi. Apropos of 3 cases].[化脓性腋窝汗腺炎的外科治疗:背阔肌肌皮岛状皮瓣的价值。附3例报告]
Ann Dermatol Venereol. 1990;117(4):277-81.
7
[Verneuil's disease in the differential diagnosis of suppuration of the ano-perineo-buttock region].
Helv Chir Acta. 1980 Sep;47(3-4):477-81.
8
[A special aspect of perianal suppuration: Verneuil's disease].
Acta Chir Belg. 1985 Sep-Oct;85(5):319-23.
9
[Chronic suppurative hidradenitis of the genito-femoral region].[慢性化脓性股生殖器区域汗腺炎]
Ugeskr Laeger. 1983 Feb 28;145(9):660-1.
10
[Hidradenitis suppurativa involving the perineal region].[累及会阴区的化脓性汗腺炎]
Harefuah. 1991 Jan 15;120(2):74-6.

引用本文的文献

1
European S2k guidelines for hidradenitis suppurativa/acne inversa part 2: Treatment.欧洲化脓性汗腺炎/反向性痤疮S2k指南第2部分:治疗
J Eur Acad Dermatol Venereol. 2025 May;39(5):899-941. doi: 10.1111/jdv.20472. Epub 2024 Dec 19.
2
Emerging Treatments and the Clinical Trial Landscape for Hidradenitis Suppurativa-Part II: Procedural and Wound Care Therapies.化脓性汗腺炎的新兴治疗方法与临床试验概况 - 第二部分:手术及伤口护理疗法
Dermatol Ther (Heidelb). 2023 Aug;13(8):1699-1720. doi: 10.1007/s13555-023-00957-5. Epub 2023 Jul 4.
3
Surgical Treatment in Hidradenitis Suppurativa.
化脓性汗腺炎的手术治疗
J Clin Med. 2022 Apr 21;11(9):2311. doi: 10.3390/jcm11092311.
4
Laser and Light-Based Treatment Modalities for the Management of Hidradenitis Suppurativa.激光和基于光的治疗方式在治疗化脓性汗腺炎中的应用。
Am J Clin Dermatol. 2020 Apr;21(2):237-243. doi: 10.1007/s40257-019-00491-1.