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甲下鳞状细胞癌:放疗作为一种替代截肢的方法,并对文献进行回顾。

Subungual squamous cell carcinoma: radiation therapy as an alternative to amputation and review of the literature.

机构信息

Department of Radiation Oncology, Willis Knighton Cancer Center, Shreveport, Louisiana 71115, USA.

出版信息

Am J Clin Dermatol. 2010;11(4):285-8. doi: 10.2165/11311080-000000000-00000.

Abstract

We report the outcomes of three patients who were treated with external beam radiotherapy as an alternative to distal phalanx amputation for subungual squamous cell carcinomas between December 2004 and September 2006. The patients' ages ranged from 46 to 83 years and the median follow-up time was 48 months (range: 36-52 months). As of the current date, the three patients show no signs of recurrence following a course of external beam radiotherapy. Complete function of the treated digit was obtained in all three patients. Irradiation should be considered as an alternative modality choice in the treatment of subungual squamous cell carcinoma in lieu of distal phalanx amputation.

摘要

我们报告了 3 例患者的治疗结果,他们在 2004 年 12 月至 2006 年 9 月期间接受了外部束放射治疗,替代了远节指骨切除术,用于治疗甲下鳞状细胞癌。患者年龄在 46 至 83 岁之间,中位随访时间为 48 个月(范围:36-52 个月)。截至目前,3 例患者在接受了一疗程的外部束放射治疗后均未出现复发迹象。所有 3 例患者的受治疗指均完全保留了功能。在替代远节指骨切除术治疗甲下鳞状细胞癌时,放射治疗应被视为一种可供选择的治疗模式。

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