Department of Pediatrics and Department of Microbiology and Immunology, University of Arkansas for Medical Sciences and the Arkansas Children's Hospital, Little Rock, AR 72205, USA.
Expert Rev Anti Infect Ther. 2010 Feb;8(2):175-81. doi: 10.1586/eri.09.130.
In children, osteomyelitis is primarily hematogenous in origin and acute in nature. The principal cause of osteomyelitis in children is Staphylococcus aureus, and both the epidemiology and pathogenesis of S. aureus infections, including osteomyelitis, have changed in recent years owing to the emergence of community-associated methicillin-resistant S. aureus. This review focuses on advances in the diagnosis and overall management of acute hematogenous osteomyelitis in children with these changes in mind.
在儿童中，骨髓炎主要是血源性的，且性质为急性。儿童骨髓炎的主要病因是金黄色葡萄球菌，近年来，由于社区相关性耐甲氧西林金黄色葡萄球菌的出现，金黄色葡萄球菌感染（包括骨髓炎）的流行病学和发病机制发生了变化。本综述重点关注在这些变化背景下，考虑到这些变化，如何改进儿童急性血源性骨髓炎的诊断和整体管理。
