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一名患有远端腓骨急性血源性骨髓炎和感染性心内膜炎的儿童。

A Child With Acute Hematogenous Osteomyelitis of the Distal Fibula and Infective Endocarditis.

作者信息

Saadana Jacem, Lassioued Oussama, Abid Said, Ben Mansour Maha, Abid Abderrazek

机构信息

Orthopaedics and Traumatology, Fattouma Bourguiba University Hospital, Monastir, TUN.

Anesthesiology and Reanimation, Fattouma Bourguiba University Hospital, Monastir, TUN.

出版信息

Cureus. 2023 Feb 24;15(2):e35429. doi: 10.7759/cureus.35429. eCollection 2023 Feb.

DOI:10.7759/cureus.35429
PMID:36987464
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10040252/
Abstract

Acute hematogenous osteomyelitis (AHO) commonly interests the pediatric population. It typically affects the metaphyses of long tubular bones. However, the fibula is rarely involved. Regarding the hematogenous inoculation, this infection may be associated with distant foci. Herein, we present the case of a 10-year-old girl who was initially diagnosed with atypical AHO of the distal fibula complicated by a subperiosteal abscess. Upon admission, the child showed a severe septic condition, including embolic infective endocarditis (IE), which was responsible for multiple cerebral, renal, and splenic loci. AHO was successfully resolved with appropriate intravenous antimicrobial treatment targeting Staphylococcus aureus, surgical drainage, and debridement. Due to the complexity of the lesions and the embolic nature, the IE was also managed operatively with a mechanical prosthesis. The distal fibula is a rare and challenging location for AHO. EI co-infection should always be sought and suspected because, in such instances, it will genuinely complicate diagnostic and therapeutic management.

摘要

急性血源性骨髓炎(AHO)常见于儿童群体。它通常影响长管状骨的干骺端。然而,腓骨很少受累。关于血源性接种,这种感染可能与远处病灶有关。在此,我们报告一例10岁女孩的病例,她最初被诊断为远端腓骨非典型AHO并伴有骨膜下脓肿。入院时,患儿表现出严重的脓毒症状态,包括栓塞性感染性心内膜炎(IE),这导致了多个脑、肾和脾部位的病变。通过针对金黄色葡萄球菌的适当静脉抗菌治疗、手术引流和清创,AHO得以成功治愈。由于病变的复杂性和栓塞性质,IE也通过机械假体进行了手术治疗。远端腓骨是AHO的一个罕见且具有挑战性的发病部位。应始终寻找并怀疑存在IE合并感染,因为在这种情况下,它会真正使诊断和治疗管理复杂化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9eea/10040252/5f0d3ede2b9f/cureus-0015-00000035429-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9eea/10040252/d8f9c4b96702/cureus-0015-00000035429-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9eea/10040252/90d4ec1984b3/cureus-0015-00000035429-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9eea/10040252/5f0d3ede2b9f/cureus-0015-00000035429-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9eea/10040252/d8f9c4b96702/cureus-0015-00000035429-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9eea/10040252/90d4ec1984b3/cureus-0015-00000035429-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9eea/10040252/5f0d3ede2b9f/cureus-0015-00000035429-i03.jpg

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本文引用的文献

1
Pediatric Infective Endocarditis: A Literature Review.小儿感染性心内膜炎:文献综述
J Clin Med. 2022 Jun 5;11(11):3217. doi: 10.3390/jcm11113217.
2
Clinical Practice Guideline by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America: 2021 Guideline on Diagnosis and Management of Acute Hematogenous Osteomyelitis in Pediatrics.美国儿科传染病学会和传染病学会临床实践指南:2021 年儿科急性血源性骨髓炎诊断和治疗指南。
J Pediatric Infect Dis Soc. 2021 Sep 23;10(8):801-844. doi: 10.1093/jpids/piab027.
3
Difficulties in Diagnosis and Therapy of Infective Endocarditis in Children and Adolescents-Cohort Study.
儿童和青少年感染性心内膜炎的诊断与治疗难点——队列研究
Healthcare (Basel). 2021 Jun 19;9(6):760. doi: 10.3390/healthcare9060760.
4
Acute Hematogenous Osteomyelitis in Children.儿童急性血源性骨髓炎
Ochsner J. 2019 Summer;19(2):116-122. doi: 10.31486/toj.18.0138.
5
Bone and joint infections in infants under three months of age.三个月以下婴儿的骨与关节感染。
Acta Paediatr. 2019 May;108(5):933-939. doi: 10.1111/apa.14569. Epub 2018 Oct 9.
6
Bone and Joint Infections.骨与关节感染
Pediatr Infect Dis J. 2017 Aug;36(8):788-799. doi: 10.1097/INF.0000000000001635.
7
Paediatric bone and joint infection.小儿骨与关节感染
EFORT Open Rev. 2017 Mar 13;2(1):7-12. doi: 10.1302/2058-5241.2.160027. eCollection 2017 Jan.
8
Hematogenous Osteomyelitis in Infants and Children: Imaging of a Changing Disease.婴幼儿血源性骨髓炎:一种不断变化的疾病的影像学表现。
Radiology. 2017 Jun;283(3):629-643. doi: 10.1148/radiol.2017151929.
9
A Rare Case of Clavicle Osteomyelitis in a Child and Literature Review.儿童锁骨骨髓炎1例罕见病例及文献复习
Case Rep Pediatr. 2016;2016:8252318. doi: 10.1155/2016/8252318. Epub 2016 Dec 5.
10
Infective Endocarditis in Childhood: 2015 Update: A Scientific Statement From the American Heart Association.儿童感染性心内膜炎:2015年更新:美国心脏协会科学声明
Circulation. 2015 Oct 13;132(15):1487-515. doi: 10.1161/CIR.0000000000000298. Epub 2015 Sep 15.