Unità Operativa Complessa di Dermatologia Infettiva, Istituto Dermatologico S.Gallicano (IRCCS), Rome, Italy.
Epidemiol Infect. 2010 May;138(5):738-42. doi: 10.1017/S0950268810000130. Epub 2010 Jan 29.
To assess the prevalence of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) colonization in HIV-1-infected men who have sex with men (MSM), a cross-sectional study was conducted on 104 persons attending a large STI/HIV unit in Rome, Italy in the period June 2007-June 2008. Swabs obtained from both anterior nares and S. aureus isolates were characterized by phenotypic and genotypic methods. A total of 24 individuals (23.1%) were colonized with S. aureus but none carried MRSA. No statistically significant association between colonization with S. aureus and behavioural, clinical, virological or immunological characteristics was identified. This study indicates a lack of circulation of CA-MRSA in HIV-1-infected MSM in Italy and underscores large epidemiological differences between the USA and a European country, so that only locally conducted epidemiological studies can provide insight into the local circulation of CA-MRSA in general and selected populations.
为了评估感染人类免疫缺陷病毒 1 型（HIV-1）的男男性行为者（MSM）中社区获得性耐甲氧西林金黄色葡萄球菌（CA-MRSA）定植的流行率，在 2007 年 6 月至 2008 年 6 月期间，对意大利罗马一家大型性传播感染/艾滋病病毒（HIV）单位的 104 名患者进行了一项横断面研究。从前鼻和金黄色葡萄球菌分离物中获得拭子，并通过表型和基因型方法进行特征描述。共有 24 名个体（23.1%）定植了金黄色葡萄球菌，但均未携带 MRSA。金黄色葡萄球菌定植与行为、临床、病毒学或免疫学特征之间无统计学显著关联。本研究表明，意大利 HIV-1 感染的 MSM 中不存在 CA-MRSA 的传播，并突出了美国和欧洲国家之间的巨大流行病学差异，因此只有在当地进行的流行病学研究才能深入了解 CA-MRSA 在一般人群和特定人群中的局部传播情况。
