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B细胞淋巴瘤后莫旺综合征。

Morvan syndrome following B-cell lymphoma.

作者信息

El-Bitar Mohamad K, Muwakkit Samar A, Abboud Miguel R, Sawaya Raja A, Boustany Rose-Mary

机构信息

Division of Pediatric Neurology/Pediatric Epilepsy Program, Department of Pediatrics, American University of Beirut Medical Center, Beirut, Lebanon.

出版信息

J Child Neurol. 2010 Aug;25(8):1038-41. doi: 10.1177/0883073809356108. Epub 2010 Jan 28.

Abstract

Morvan syndrome is a rare autoimmune disease named after the French physician Augustin Marie Morvan. It is characterized by multiple, irregular contractions of the long muscles, weakness, pruritus, hyperhidrosis, insomnia, and delirium. Here, we describe a 17-year-old young man, previously diagnosed with B-cell lymphoma, who presented with multiple asynchronous fasciculations of the long muscles of his lower extremities accompanied by numbness. The patient responded initially to pulse corticosteroids with diminution of the fasciculations. He achieved complete remission following 7 consecutive, monthly intravenous immunoglobulin injections. The present case is described in the context of the available literature.

摘要

莫旺综合征是一种罕见的自身免疫性疾病,以法国医生奥古斯汀·玛丽·莫旺的名字命名。其特征为长肌出现多发性、不规则收缩,伴有无力、瘙痒、多汗、失眠和谵妄。在此,我们描述一名17岁的年轻男性,他之前被诊断患有B细胞淋巴瘤,现出现下肢长肌多发性不同步肌束震颤并伴有麻木。患者最初对冲击剂量的皮质类固醇治疗有反应,肌束震颤减轻。在连续7个月每月静脉注射免疫球蛋白后,他实现了完全缓解。本文结合现有文献对该病例进行了描述。

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