Béquet D, Devière F, Renard J L, Felten D
Service de Neurologie, Hôpital d'Instruction des Armées du Val-de-Grâce, Paris.
Rev Neurol (Paris). 1997 Oct;153(10):602-4.
A 35 year-old man developed a syndrome with muscle cramp, myokimia, generalized, fasciculations, excessive sweating, sleep disorders and severe impairment. It was a syndrome of continuous muscle fiber activity--or Isaacs syndrome--with central disorders (this may be called "Maladie de Morvan"). Previous reports have suggested that Isaac's syndrome might be an autoimmune disorder. Moreover, high doses intravenous immunoglobulins were given resulting in a substantial improvement six months after the onset of this treatment.
一名35岁男性出现了一种综合征，伴有肌肉痉挛、肌纤维颤搐、全身性肌束震颤、多汗、睡眠障碍和严重功能损害。这是一种连续肌肉纤维活动综合征——即艾萨克综合征——伴有中枢神经系统障碍（这可能被称为“莫旺氏病”）。先前的报告表明，艾萨克综合征可能是一种自身免疫性疾病。此外，给予了大剂量静脉注射免疫球蛋白，在开始这种治疗六个月后病情有了显著改善。
