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患有白鼻综合征的冬眠蝙蝠的病理发现和肝脏组织学特征。

Pathologic findings and liver elements in hibernating bats with white-nose syndrome.

机构信息

Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, CT 06269, USA.

出版信息

Vet Pathol. 2010 Mar;47(2):214-9. doi: 10.1177/0300985809358614. Epub 2010 Jan 28.

Abstract

Two groups of vespertilionid bats were collected from affected hibernacula. In group 1 (n, 14; pathology and microbiology), the average body weights of all species were at the lower limit of published ranges. Twelve bats (86%) had mycotic growth in the epidermis, hair follicles, and sebaceous glands. Geomyces destructans, with its characteristic curved conidia, was observed microscopically, cultured, and confirmed by polymerase chain reaction. Dermatitis and mural folliculitis was nil to mild. When focally coinfected with Gram-negative bacteria, there was necrosis and pustules. Fat stores were little to abundant in 12 bats (86%) and nil in 2. Thirteen bats (93%) had pulmonary congestion and 7 (50%) had bone marrow granulocytosis. In group 2 (n, 24; liver elements), 3 bats (13%) had potentially toxic lead levels and 1 (4%), potentially toxic arsenic level. There was no evidence of major organ failure or consistent element toxicity.

摘要

两组食虫蝙蝠是从受影响的冬眠地收集的。在第 1 组(n=14;病理学和微生物学)中,所有物种的平均体重都处于已发表范围的下限。12 只蝙蝠(86%)的表皮、毛囊和皮脂腺中有真菌生长。曲霉菌,其特征性的弯曲分生孢子,在显微镜下观察到、培养并通过聚合酶链反应得到证实。皮炎和壁状滤泡炎从轻度到中度。当与革兰氏阴性菌局部合并感染时,会出现坏死和脓疱。12 只蝙蝠(86%)的脂肪储存很少到丰富,2 只蝙蝠(14%)的脂肪储存为零。13 只蝙蝠(93%)有肺充血,7 只(50%)有骨髓粒细胞增多。在第 2 组(n=24;肝脏元素)中,3 只蝙蝠(13%)有潜在毒性的铅水平,1 只(4%)有潜在毒性的砷水平。没有主要器官衰竭或一致的元素毒性的证据。

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