Dept of Public Health Medicine, Graduate School of Comprehensive Human Sciences and Institute of Community Medicine, University of Tsukuba, Tsukuba, Japan.
Eur Respir J. 2010 Aug;36(2):379-84. doi: 10.1183/09031936.00118609. Epub 2010 Jan 28.
The aim of the present study was to compare the prevalence of sleep-disordered breathing among Hispanic and white Americans and Japanese. A 1-night sleep study using a single-channel airflow monitor was performed on 211 Hispanics and 246 Whites from the Minnesota field centre (St Paul, MN, USA) of the Multi-Ethnic Study of Atherosclerosis (MESA), and 978 Japanese from three community-based cohorts of the Circulatory Risk in Communities Study (CIRCS) in Japan. The respiratory disturbance index and sleep-disordered breathing, defined as a respiratory disturbance index of > or =15 events x h(-1), were estimated. The prevalence of sleep-disordered breathing was higher in males (34.2%) than females (14.7%), and among Hispanics (36.5%) and Whites (33.3%) than among Japanese (18.4%), corresponding to differences in body mass index. Within body mass index strata, the race difference in sleep-disordered breathing was attenuated. This was also true when body mass index was adjusted for instead of stratification. The strong association between body mass index and sleep-disordered breathing was similar in Japanese and Americans. The prevalence of sleep-disordered breathing was lower among Japanese than among Americans. However, the association of body mass index with sleep-disordered breathing was strong, and similar among the race/ethnic groups studied. The majority of the race/ethnic difference in sleep-disordered breathing prevalence was explained by a difference in body mass index distribution.
本研究旨在比较 Hispanic 裔、美国白种人和日本人睡眠呼吸紊乱的患病率。对来自美国明尼苏达州圣保罗市（MN）多发性动脉硬化症多民族研究（MESA）的 211 名 Hispanic 裔和 246 名白种人，以及来自日本 Circulatory Risk in Communities Study（CIRCS）三个社区队列的 978 名日本人进行了为期 1 晚的睡眠研究，使用单通道气流监测仪。呼吸紊乱指数和睡眠呼吸紊乱的定义为呼吸紊乱指数 > 或 = 15 次 x h(-1)。睡眠呼吸紊乱的患病率在男性（34.2%）高于女性（14.7%），在 Hispanic 裔（36.5%）和白种人（33.3%）高于日本人（18.4%），这与体重指数有关。在体重指数分层内，睡眠呼吸紊乱的种族差异减弱。当用体重指数代替分层进行调整时，这种情况也是如此。体重指数与睡眠呼吸紊乱之间的强相关性在日本人和美国人中是相似的。日本人睡眠呼吸紊乱的患病率低于美国人。然而，体重指数与睡眠呼吸紊乱的相关性很强，并且在研究的种族/民族群体中相似。睡眠呼吸紊乱患病率的大部分种族/民族差异可以用体重指数分布的差异来解释。
