Covington Derek B, Rosenblum Marc K, Brathwaite Carole D, Sandberg David I
Department of Neurological Surgery, Miller School of Medicine, University of Miami, and Miami Children's Hospital, Miami, FL 33155, USA.
Pediatr Neurosurg. 2009;45(6):429-33. doi: 10.1159/000277616. Epub 2010 Jan 26.
Angiocentric glioma, a rare brain neoplasm with features of ependymal differentiation, has only recently been recognized as a distinct clinicopathological entity. To date, all reported cases have involved tumors in the cerebral hemispheres, and the majority have presented with seizures. The authors report the case of a 5-year-old girl who presented with several cranial neuropathies and mild gait disturbance. An exophytic neoplasm arising from the posterior midbrain and causing obstructive hydrocephalus was identified, and surgical resection revealed a neoplasm with features of angiocentric glioma.
血管中心性胶质瘤是一种具有室管膜分化特征的罕见脑肿瘤，直到最近才被确认为一种独特的临床病理实体。迄今为止，所有报道的病例均累及大脑半球的肿瘤，且大多数表现为癫痫发作。作者报告了一名5岁女孩的病例，该女孩表现为多种颅神经病变和轻度步态障碍。发现一个起源于中脑后部的外生性肿瘤并导致梗阻性脑积水，手术切除显示该肿瘤具有血管中心性胶质瘤的特征。
