Heuer Gregory G, Jackson Eric M, Magge Suresh N, Storm Phillip B
Children's Hospital of Philadelphia, Division of Neurosurgery, Wood Center, 6 Floor, Philadelphia, PA 19104, USA.
Expert Rev Anticancer Ther. 2007 Dec;7(12 Suppl):S61-8. doi: 10.1586/14737140.7.12s.S61.
Brain tumors are the most common cause of cancer-related death and the second most common form of cancer in pediatric patients. Many of these tumors are treated primarily with surgery, either alone or in combination with radiation or chemotherapy. Recent advances have lead to greater survival and decreased morbidities in childhood brain tumor patients. A full understanding of the biology and primary treatment modalities for the particular tumor are essential for any professional treating these patients, including the neurosurgeon. Each tumor type has features in common with, and unique from, other tumors that need to be understood prior to undertaking a rational treatment plan. This article summarizes some of these features.
脑肿瘤是儿童患者癌症相关死亡的最常见原因,也是第二常见的癌症形式。这些肿瘤大多主要通过手术治疗,单独手术或与放疗或化疗联合使用。最近的进展已使儿童脑肿瘤患者的生存率提高,发病率降低。对于任何治疗这些患者的专业人员,包括神经外科医生来说,全面了解特定肿瘤的生物学特性和主要治疗方式至关重要。在制定合理的治疗方案之前,每种肿瘤类型都有与其他肿瘤相同和独特的特征,需要加以了解。本文总结了其中一些特征。