Angiocentric glioma with MYB-QKI fusion located in the brainstem, rather than cerebral cortex.
作者信息
Chan Emily, Bollen Andrew W, Sirohi Deepika, Van Ziffle Jessica, Grenert James P, Kline Cassie N, Tihan Tarik, Perry Arie, Gupta Nalin, Solomon David A
机构信息
Department of Pathology, University of California, San Francisco, 513 Parnassus Ave, Health Sciences West 451, San Francisco, CA, 94143, USA.
Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, USA.
出版信息
Acta Neuropathol. 2017 Oct;134(4):671-673. doi: 10.1007/s00401-017-1759-x. Epub 2017 Aug 3.
Abstract
摘要
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本文引用的文献
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Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy.对儿科神经肿瘤患者进行靶向二代测序可改善诊断、识别致病性种系突变并指导靶向治疗。
Neuro Oncol. 2017 May 1;19(5):699-709. doi: 10.1093/neuonc/now254.
2
MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism.血管中心性胶质瘤中的MYB-QKI重排通过三方机制驱动肿瘤发生。
Nat Genet. 2016 Mar;48(3):273-82. doi: 10.1038/ng.3500. Epub 2016 Feb 1.
3
Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology.罕见低级别神经上皮肿瘤中的基因改变：BRAF、FGFR1和MYB突变高频发生且与形态学相符。
Acta Neuropathol. 2016 Jun;131(6):833-45. doi: 10.1007/s00401-016-1539-z. Epub 2016 Jan 25.
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Clinical attributes and surgical outcomes of angiocentric gliomas.血管中心性胶质瘤的临床特征与手术结果
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Angiocentric glioma-like tumor of the midbrain.中脑的血管中心性胶质瘤样肿瘤。
Pediatr Neurosurg. 2009;45(6):429-33. doi: 10.1159/000277616. Epub 2010 Jan 26.
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The 2007 WHO classification of tumours of the central nervous system.2007年世界卫生组织中枢神经系统肿瘤分类
Acta Neuropathol. 2007 Aug;114(2):97-109. doi: 10.1007/s00401-007-0243-4. Epub 2007 Jul 6.
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Monomorphous angiocentric glioma: a distinctive epileptogenic neoplasm with features of infiltrating astrocytoma and ependymoma.单形性血管中心性胶质瘤：一种具有浸润性星形细胞瘤和室管膜瘤特征的独特致痫性肿瘤。
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