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Angiocentric glioma with MYB-QKI fusion located in the brainstem, rather than cerebral cortex.

作者信息

Chan Emily, Bollen Andrew W, Sirohi Deepika, Van Ziffle Jessica, Grenert James P, Kline Cassie N, Tihan Tarik, Perry Arie, Gupta Nalin, Solomon David A

机构信息

Department of Pathology, University of California, San Francisco, 513 Parnassus Ave, Health Sciences West 451, San Francisco, CA, 94143, USA.

Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, USA.

出版信息

Acta Neuropathol. 2017 Oct;134(4):671-673. doi: 10.1007/s00401-017-1759-x. Epub 2017 Aug 3.

DOI:10.1007/s00401-017-1759-x
PMID:28776091
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5693679/
Abstract
摘要

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本文引用的文献

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Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy.对儿科神经肿瘤患者进行靶向二代测序可改善诊断、识别致病性种系突变并指导靶向治疗。
Neuro Oncol. 2017 May 1;19(5):699-709. doi: 10.1093/neuonc/now254.
2
MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism.血管中心性胶质瘤中的MYB-QKI重排通过三方机制驱动肿瘤发生。
Nat Genet. 2016 Mar;48(3):273-82. doi: 10.1038/ng.3500. Epub 2016 Feb 1.
3
Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology.
血管中心性胶质瘤患者的临床特征及MYB-QKI融合的检测
Neurol Sci. 2025 Jan;46(1):427-436. doi: 10.1007/s10072-024-07721-3. Epub 2024 Aug 5.
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Case Report: Brainstem angiocentric glioma presenting in a toddler child-diagnostic and therapeutic challenges.病例报告：婴儿期脑干血管中心性胶质瘤-诊断和治疗挑战。
Pathol Oncol Res. 2023 Jun 9;29:1611231. doi: 10.3389/pore.2023.1611231. eCollection 2023.
5
DIPG-like MYB-altered diffuse astrocytoma with durable response to intensive chemotherapy.DIPG 样 MYB 改变弥漫性星形细胞瘤对强化化疗有持久反应。
Childs Nerv Syst. 2023 Sep;39(9):2509-2513. doi: 10.1007/s00381-023-05976-3. Epub 2023 May 11.
6
Treatment of Pediatric Low-Grade Gliomas.小儿低级别胶质瘤的治疗。
Curr Neurol Neurosci Rep. 2023 Apr;23(4):185-199. doi: 10.1007/s11910-023-01257-3. Epub 2023 Mar 7.
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MYB/MYBL1::QKI fusion-positive diffuse glioma.MYB/MYBL1::QKI 融合阳性弥漫性胶质瘤。
J Neuropathol Exp Neurol. 2023 Feb 21;82(3):250-260. doi: 10.1093/jnen/nlac123.
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2021 WHO classification of tumours of the central nervous system: a review for the neuroradiologist.2021 年世界卫生组织中枢神经系统肿瘤分类：神经放射学家的复习指南。
Neuroradiology. 2022 Oct;64(10):1919-1950. doi: 10.1007/s00234-022-03008-6. Epub 2022 Jul 22.
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