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非相邻双四氢呋喃和非相邻四氢呋喃-四氢吡喃亚类番荔枝烷型乙酰基生物合成。

Total synthesis of annonaceous acetogenins belonging to the non-adjacent bis-THF and non-adjacent THF-THP sub-classes.

机构信息

The School of Chemistry, The University of Southampton, Highfield, Southampton SO171BJ, UK.

出版信息

Molecules. 2010 Jan 21;15(1):460-501. doi: 10.3390/molecules15010460.

DOI:10.3390/molecules15010460
PMID:20110904
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6257053/
Abstract

The synthesis of the subgroups of acetogenins containing non-adjacent bis-THF and non-adjacent THF-THP core units is reviewed. Specifically, total syntheses of gigantecin, 4-deoxygigantecin, cis-sylvaticin, squamostatin-C, squamostatin-D, sylvaticin and mucocin are discussed.

摘要

本文综述了含有非相邻双-THF 和非相邻 THF-THP 核单元的乙酰二萜类化合物亚组的合成。具体讨论了 gigantecin、4-去氧 gigantecin、cis-sylvaticin、squamostatin-C、squamostatin-D、sylvaticin 和 mucocin 的全合成。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9081/6257053/80462eeb652e/molecules-15-00460-g042.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9081/6257053/d96a6a1ec3f2/molecules-15-00460-g027.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9081/6257053/e7fc0b4adc3c/molecules-15-00460-g028.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9081/6257053/e8b1343b614f/molecules-15-00460-g029.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9081/6257053/9d18fb9763ac/molecules-15-00460-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9081/6257053/f9c664f69781/molecules-15-00460-g030.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9081/6257053/9c005f64fb81/molecules-15-00460-g031.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9081/6257053/03321938fd7e/molecules-15-00460-g032.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9081/6257053/eb91916242b3/molecules-15-00460-g033.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9081/6257053/44dfc5ebafb9/molecules-15-00460-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9081/6257053/4c56ef34ab1b/molecules-15-00460-g034.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9081/6257053/d6001cc89379/molecules-15-00460-g035.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9081/6257053/5b6168bf8f27/molecules-15-00460-g036.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9081/6257053/aa9b632dcb3d/molecules-15-00460-g038.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9081/6257053/935d2259d2a7/molecules-15-00460-g041.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9081/6257053/80462eeb652e/molecules-15-00460-g042.jpg

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