Department of Cardiology, Medical Centre Alkmaar, Alkmaar, the Netherlands.
Neth Heart J. 2010 Jan;18(1):7-11.
Background. The current treatment of choice in patients with three-vessel coronary disease is coronary artery bypass grafting. The use of the left internal mammary artery in bypass grafting has shown superior long-term outcomes compared with venous grafting. In our study we assess the safety and feasibility of all-arterial coronary artery bypass graft surgery using the procedure as described by Tector et al. in 2001.Methods. Between June 2001 and February 2007, we studied 133 patients eligible for non-emergency surgical revascularisation. Primary endpoints were death or re-infarction within a 30-day period. Secondary endpoints were the need for emergency coronary surgery, angioplasty and mediastinitis. Long-term follow-up had a mean duration of 33 months postoperatively.Results. All 133 patients were successfully revascularised, 98% with the off-pump technique. In 93% of the patients (n=124) full arterial grafting was achieved using both internal mammary arteries. Thirty-day mortality was 1.5% (n=2), ten re-thoracotomies were performed, one myocardial infarction and one case of mediastinitis were reported. In the next four years six additional patients died. Most of these deaths were due to non-cardiovascular causes. Two patients required angioplasty because of distal bypass graft failure and one for new native coronary artery disease. Conclusion. All-arterial bypass grafting using both internal mammary arteries with the technique as described by Tector is safe and feasible without excess deep sternal wound infections. Late major adverse cardiac events are rare and due to distal graft dysfunction, which can be treated by percutaneous coronary intervention. (Neth Heart J 2010;18:7-11.).
目前三血管病变患者的治疗选择是冠状动脉旁路移植术。与静脉桥相比,左内乳动脉在旁路移植术中显示出更好的长期效果。在我们的研究中,我们评估了 2001 年 Tector 等人描述的全动脉冠状动脉旁路移植手术的安全性和可行性。
2001 年 6 月至 2007 年 2 月,我们研究了 133 名符合非紧急手术血运重建条件的患者。主要终点是 30 天内死亡或再梗死。次要终点是需要紧急冠状动脉手术、血管成形术和纵隔炎。长期随访的平均时间为术后 33 个月。
所有 133 名患者均成功进行了血运重建,98%的患者采用非体外循环技术。93%的患者(n=124)采用双侧内乳动脉实现了全动脉搭桥。30 天死亡率为 1.5%(n=2),10 例开胸再次手术,1 例心肌梗死,1 例纵隔炎。在接下来的四年中,又有 6 名患者死亡。这些死亡大多是非心血管原因造成的。两名患者因远端旁路移植失败和一名患者因新的原发性冠状动脉疾病需要血管成形术。
采用 Tector 描述的技术使用双侧内乳动脉进行全动脉旁路移植术是安全可行的,不会增加深部胸骨伤口感染的风险。晚期主要不良心脏事件很少见,是由于远端移植物功能障碍所致,可以通过经皮冠状动脉介入治疗来治疗。(荷兰心脏杂志 2010;18:7-11)。