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左主干冠状动脉血栓远端栓塞致急性心肌梗死 1 例。

A case of acute myocardial infarction caused by distal embolization of a left main coronary artery thrombus.

机构信息

Division of Cardiology, Daegu Catholic University Medical Center, Daegu, Korea.

出版信息

Korean Circ J. 2010 Jan;40(1):46-9. doi: 10.4070/kcj.2010.40.1.46. Epub 2010 Jan 27.

Abstract

Coronary embolism is an uncommon cause of myocardial infarction. A 48-year-old male presented with typical chest pain of an MI. There was no definite ST segment change on electrocardiogram (ECG) and no elevation of myocardial enzymes. Coronary angiography (CAG) revealed occlusion of the distal left anterior descending coronary artery (dLAD), the distal left circumflex coronary artery (dLCX), the diagonal branch (D) and the obtuse marginal branch (OM), with a large filling defect in the left main coronary artery (LMA) that caused the myocardial infarction. We considered the possibility that coronary embolization was caused by the migration of a thrombus in the LMA during CAG. We did balloon angioplasty in the dLAD, dLCX, OM and D and treated the patient with glycoprotein IIb/IIIa receptor antagonist. However, thrombi remained in the dLAD, OM, and dLCX. After 3 days of anti-thrombotic treatment, follow-up CAG revealed only slight resolution of thrombi in the LAD. After triple antiplatelet agent medication for 1 year, a follow-up CAG showed a resolution of the thrombi in all coronary arteries.

摘要

冠状动脉栓塞是心肌梗死的一个不常见原因。一名 48 岁男性出现典型的心肌梗死胸痛。心电图(ECG)上没有明确的 ST 段改变,心肌酶也没有升高。冠状动脉造影(CAG)显示左前降支(dLAD)、左回旋支(dLCX)、对角支(D)和钝缘支(OM)的远端闭塞,左主干(LMA)内有大的充盈缺损,导致心肌梗死。我们考虑 CAG 过程中 LMA 内血栓迁移引起冠状动脉栓塞的可能性。我们在 dLAD、dLCX、OM 和 D 进行了球囊血管成形术,并使用糖蛋白 IIb/IIIa 受体拮抗剂治疗患者。然而,dLAD、OM 和 dLCX 仍有血栓。抗血栓治疗 3 天后,随访 CAG 显示 LAD 内血栓仅略有缓解。三联抗血小板治疗 1 年后,随访 CAG 显示所有冠状动脉内的血栓均已溶解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38ea/2812798/170c97b9c394/kcj-40-46-g001.jpg

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