Department of Cardiology, China-Japan Union Hospital of Jilin University, Jilin Provincial Engineering Laboratory for Endothelial Function and Genetic Diagnosis of Cardiovascular Disease, Jilin Provincial Cardiovascular Research Institute, Xiantai Street NO.126, Changchun, Jilin, China.
BMC Cardiovasc Disord. 2018 Dec 10;18(1):228. doi: 10.1186/s12872-018-0951-9.
The failure of aspiration thrombectomy may negatively impact outcomes in patients with acute myocardial infarction (AMI), but the available options are limited.
A 41-year-old man with chest pain for 2 h presented with ST-segment elevation myocardial infarction. Coronary angiography revealed a large filling defect extending from the distal left main (LM) coronary artery into the proximal left circumflex (LCX) coronary artery. The whole thrombus moved and occluded the proximal left anterior descending (LAD) artery, while the guidewire crossed the lesion. Dedicated manual aspiration thrombectomy (MAT) and balloon dilation failed to reduce thrombus burden. We considered thrombus extraction as impossible when it moved forward to occlude the middle LAD. To reduce infarct size, a new balloon-pushing technique was successfully performed to move the thrombus to the terminal LAD based on the actual condition of the LAD. The final angiogram demonstrated no stenosis in the LM artery and stent deployment was not performed. A 1-week follow-up coronary angiography revealed the complete resolution of thrombus and flow restoration in the left coronary artery. Intravascular ultrasound (IVUS) showed nonsignificant residual stenosis of the LM artery. No adverse events occurred during a 12-month follow-up period.
This case suggests that the new balloon-pushing technique is a useful remedy if repeated MAT fails during AMI.
抽吸血栓切除术的失败可能会对急性心肌梗死(AMI)患者的预后产生负面影响,但目前可用的选择有限。
一名 41 岁男性因胸痛 2 小时就诊,心电图显示 ST 段抬高型心肌梗死。冠状动脉造影显示从左主干(LM)远端延伸至左回旋支(LCX)近端的大充盈缺损。整个血栓移动并阻塞了近端前降支(LAD),而导丝穿过了病变部位。专用手动抽吸血栓切除术(MAT)和球囊扩张未能降低血栓负荷。当血栓向前移动阻塞了中间 LAD 时,我们认为血栓提取是不可能的。为了减少梗死面积,根据 LAD 的实际情况,成功地采用了一种新的球囊推送技术将血栓推向终末 LAD。最终的血管造影显示 LM 动脉无狭窄,未进行支架置入。1 周的随访冠状动脉造影显示血栓完全溶解,左冠状动脉血流恢复。血管内超声(IVUS)显示 LM 动脉无明显残余狭窄。在 12 个月的随访期间未发生不良事件。
如果 AMI 期间重复 MAT 失败,这种新的球囊推送技术是一种有用的补救方法。