Department of Chemistry and Biochemistry, University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland.
Chem Soc Rev. 2010 Feb;39(2):410-22. doi: 10.1039/b910030j. Epub 2009 Dec 8.
The rational formation of aromatic chromophore arrays is an intriguing challenge since ordered collectives of chromophores possess properties that are largely different from those of the individual molecules. Therefore, nucleic acids are increasingly used as scaffolds for the construction of multi-chromophore arrays. This tutorial review provides an introduction to the field of nucleic acid-guided chromophore assemblies for non-specialists and a reference point for those familiar with the area by highlighting the recent developments and describing some of the spectroscopic methods used for the study of oligonucleotide-chromophore conjugates.
芳香族生色团阵列的合理形成是一个有趣的挑战,因为生色团的有序集体具有与单个分子大不相同的性质。因此,核酸越来越多地被用作构建多生色团阵列的支架。本教程综述为非专业人士介绍了核酸指导的生色团组装领域,并为熟悉该领域的人提供了一个参考点,重点介绍了最近的发展,并描述了用于研究寡核苷酸-生色团缀合物的一些光谱方法。