Department of Occupational Medicine, Idrija Mercury Mine, Idrija, Slovenia.
Am J Ind Med. 2010 May;53(5):535-47. doi: 10.1002/ajim.20798.
The Idrija Mercury Mine (1490-1994) appointed its first physician, Joannes Antonius Scopoli, in 1754. Most of his descriptions of mercurialism are still relevant today. This study highlights Scopoli's observations on the interaction between elemental mercury (Hg degrees ) and alcohol, on the appearance of lung impairment, insomnia, and depressive mood in mercurialism. This presentation is based on Scopoli's experiences presented in his book, De Hydrargyro Idriensi Tentamina (1761), current knowledge, and our own experience acquired through health monitoring of occupational Hg degrees exposure. Some studies have confirmed Scopoli's observation that alcohol enhances mercurialism and his hypothesis that exposure to high Hg degrees concentrations causes serious lung impairment. Neurobiological studies have highlighted the influence of Hg degrees on sleep disorder and depressive mood observed by Scopoli. Although today's knowledge provides new perspectives of Scopoli's work on mercurialism, his work is still very important and can be considered a part of occupational medicine heritage.
伊德里亚汞矿（1490-1994 年）于 1754 年任命了其第一位医生，乔瓦尼·安东尼奥·斯科普利（Joannes Antonius Scopoli）。他对汞中毒的大部分描述在今天仍然适用。本研究强调了斯科普利对元素汞（Hg0）与酒精相互作用、汞中毒导致肺部损伤、失眠和抑郁情绪的观察。本报告基于斯科普利在他的著作《De Hydrargyro Idriensi Tentamina》（1761 年）中所描述的经验、当前的知识以及我们通过职业性汞暴露健康监测获得的经验。一些研究证实了斯科普利关于酒精增强汞中毒的观察结果，以及他关于暴露于高浓度汞会导致严重肺部损伤的假设。神经生物学研究强调了汞对斯科普利观察到的睡眠障碍和抑郁情绪的影响。尽管当今的知识为斯科普利关于汞中毒的工作提供了新的视角，但他的工作仍然非常重要，可以被视为职业医学遗产的一部分。
