Department of Surgery, Chonbuk National University Medical School, Jeonju, South Korea.
Clin Anat. 2010 Apr;23(3):297-303. doi: 10.1002/ca.20930.
The retrohepatic inferior vena cava (IVC) is commonly considered to originate from the right vitelline or omphalomesenteric vein. In contrast, Alexander Barry hypothesized that one of the hepatic veins grows to merge with the subcardinal vein and develops into the retrohepatic IVC. We re-examined fetal development of the retrohepatic IVC and other related veins using serial histological sections of 20 human fetuses between 6 and 16 weeks of gestation. At 6-7 weeks, when a basic configuration of the portal-hepatic vein systems had just been established, one of hepatic veins (i.e., the posterocaudal vein in the present study) had grown caudally to reach the posterocaudal surface of the liver, and notably, extended into the primitive right adrenal gland (five of the eight early-staged fetuses). Because the inferior right hepatic vein (IRHV) and retrohepatic IVC appeared at the same developmental stage, it is likely that any peripheral remnants of the posterocaudal vein would continue to function as primary drainage territory for the IRHV. The caudate vein developed rapidly in accordance with marked caudal and leftward extension of Spiegel's lobe at 12-16 weeks. Thin accessory hepatic veins developed later than the caudate vein and IRHV. The present results supported Barry's hypothesis.
肝后下腔静脉（IVC）通常被认为起源于右脐静脉或卵黄肠系膜静脉。相比之下，Alexander Barry 假设其中一条肝静脉生长并与心侧静脉合并，发育成肝后 IVC。我们使用 20 例 6 至 16 周胎龄胎儿的连续组织学切片重新检查了肝后 IVC 和其他相关静脉的胚胎发育。在 6-7 周时，当门静脉 - 肝静脉系统的基本结构刚刚建立时，一条肝静脉（即本研究中的后尾静脉）已经向尾侧生长，到达肝脏的后尾侧表面，并且值得注意的是，延伸到原始右肾上腺（8 例早期胎龄中的 5 例）。由于右肝下静脉（IRHV）和肝后 IVC 出现在相同的发育阶段，因此后尾静脉的任何周围残端很可能继续作为 IRHV 的主要引流区域。在 12-16 周时，Spiegel 叶的明显尾侧和左向延伸，尾状叶迅速发育。薄的副肝静脉比尾状叶静脉和 IRHV 发育得晚。本研究结果支持 Barry 的假设。
