Lan Tian, Wang Yang-min, Chen Ye
Department of Urology, Lanzhou General Hospital of Lanzhou Military Region, Lanzhou, Gansu 730050, China.
Zhonghua Nan Ke Xue. 2009 Oct;15(10):886-90.
To investigate the prevalence and characteristics of sexual dysfunction in patients with chronic prostatitis (CP) in the high altitude area.
A total of 637 CP patients randomly recruited from different urologic clinics were divided into 4 groups according to their living altitudes. The subjects were scored on the National Institute of the Health Chronic Prostatitis Symptom Index (NIH-CPSI), the International Index of Erectile Function-5 (IIEF-5), the Chinese Index of Sexual Function for Premature Ejaculation (C-ISFPE) and the questionnaire on ejaculatory difficulties from the University of Washington Symptom Score.
In the 637 CP patients, the overall incidences of premature ejaculation (PE), erectile dysfunction (ED) and difficult ejaculation (DE) were 28.4%, 17.6% and 23.9%, respectively, 9.9% with PE, ED and DE simultaneously. With the increase of the living altitude, the scores on IIEF-5 (P = 0.032) and C-ISFPE (P = 0. 047) were obviously decreased, and the incidences of PE (P = 0.047), ED (P = 0.046) and DE (P = 0.019) markedly elevated. Those with PE or ED experienced worse symptoms at a higher altitude (r = 0.249 or 0.267, P < 0.05). The differences were all statistically significant.
The prevalence and severity of sexual dysfunction are positively correlated with the living altitude among CP patients.
探讨高海拔地区慢性前列腺炎（CP）患者性功能障碍的患病率及特点。
从不同泌尿外科诊所随机招募637例CP患者，根据其居住海拔分为4组。采用美国国立卫生研究院慢性前列腺炎症状指数（NIH-CPSI）、国际勃起功能指数-5（IIEF-5）、中国早泄性功能指数（C-ISFPE）及华盛顿大学症状评分中的射精困难问卷对研究对象进行评分。
637例CP患者中，早泄（PE）、勃起功能障碍（ED）和射精困难（DE）的总体发生率分别为28.4%、17.6%和23.9%，同时存在PE、ED和DE的比例为9.9%。随着居住海拔的升高，IIEF-5评分（P = 0.032）和C-ISFPE评分（P = 0.047）明显降低，PE（P = 0.047）、ED（P = 0.046）和DE（P = 0.019）的发生率显著升高。存在PE或ED的患者在海拔较高时症状更严重（r = 0.249或0.267，P < 0.05）。差异均具有统计学意义。
CP患者性功能障碍的患病率及严重程度与居住海拔呈正相关。
