Division of Nephrology, Department of Internal Medicine, School of Medicine, Ewha Womans University, Seoul, South Korea.
Ren Fail. 2010 Jan;32(1):139-42. doi: 10.3109/08860220903391218.
Granulomatous interstitial nephritis (GIN) is a rare disease. Contributing factors such as drugs, sarcoidosis, infections, and paraproteinemia have been reported, and when no obvious contributing factors can be identified, the disease is classified as idiopathic GIN. We managed a patient with idiopathic GIN with an unusually large granuloma. Usually, granulomas are smaller or slightly larger than glomeruli. However, our patient had an atypical granuloma, and such a large granuloma has never been reported. GIN can be treated with steroids, and our patient improved after high-dose steroid treatment.
肉芽肿性间质性肾炎（GIN）是一种罕见疾病。据报道，其发病因素包括药物、肉样瘤病、感染和副蛋白血症等，当无法明确病因时，则将该病归类为特发性 GIN。我们曾治疗过一例特发性 GIN 患者，其表现为非常大的肉芽肿。通常，肉芽肿比肾小球稍小或稍大。然而，我们的患者存在非典型肉芽肿，且如此大的肉芽肿从未有过报道。GIN 可采用类固醇治疗，我们的患者在大剂量类固醇治疗后病情得到改善。
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