Department of Dermatology, DermaClinic, Genk, Belgium.
J Eur Acad Dermatol Venereol. 2010 Aug;24(8):867-74. doi: 10.1111/j.1468-3083.2009.03553.x. Epub 2010 Jan 22.
In 1945, Martorell described ischaemic leg ulcers in patients with hypertension. He suggested that the ischaemic necrosis was secondary to a hypertensive arteriolar disease and referred to them as 'hypertensive ischaemic ulcers'. In recent years, the specific entity of these ulcers has been questioned. Others claim they have a much higher incidence, but presume the diagnosis is frequently missed. Almost 900 cases of Martorell's ulcers have been reported in literature since the first description. A systematic review and comprehensive search of literature (evidence-based) was needed to characterize this type of ulcer. Based on aetiology and histopathology, it seems to be justified to maintain the name 'arteriolosclerotic ulcer of Martorell'. We conclude that the arteriolosclerotic ulcer of Martorell is a specific entity with its own clinical and histological diagnostic keys, wound management and preventive measures. We introduce a set of criteria that may be used to facilitate diagnosing arteriolosclerotic ulcer of Martorell as well as a flowchart that includes diagnosis, treatment and prevention of this particular type of vascular leg ulcer.
1945 年,Martorell 描述了高血压患者的缺血性腿部溃疡。他认为缺血性坏死是高血压小动脉疾病的继发性疾病,并将其称为“高血压性缺血性溃疡”。近年来,这些溃疡的具体实体受到了质疑。其他人则声称它们的发病率更高,但推测这种诊断经常被遗漏。自首次描述以来,文献中已经报道了近 900 例 Martorell 溃疡。为了描述这种类型的溃疡,需要进行系统的综述和全面的文献搜索(基于证据)。基于病因和组织病理学,保留“Martorell 小动脉粥样硬化性溃疡”的名称似乎是合理的。我们得出结论,Martorell 的小动脉粥样硬化性溃疡是一种具有自身临床和组织学诊断特征、伤口管理和预防措施的特定实体。我们提出了一套可能有助于诊断 Martorell 小动脉粥样硬化性溃疡的标准,并提出了一个流程图,包括这种特殊类型的血管性腿部溃疡的诊断、治疗和预防。