使用改进的最小二乘 Prony 方法对松质骨中双组分超声脉冲的分解 - 幻影实验和模拟。
Decomposition of two-component ultrasound pulses in cancellous bone using modified least squares prony method--phantom experiment and simulation.
机构信息
Center for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA.
出版信息
Ultrasound Med Biol. 2010 Feb;36(2):276-87. doi: 10.1016/j.ultrasmedbio.2009.06.1092.
Porous media such as cancellous bone often support the simultaneous propagation of two compressional waves. When small bone samples are interrogated in through-transmission with broadband sources, these two waves often overlap in time. The modified least-squares Prony's (MLSP) method was tested for decomposing a 500 kHz-center-frequency signal containing two overlapping components: one passing through a polycarbonate plate (to produce the "fast" wave) and another passing through a cancellous-bone-mimicking phantom (to produce the "slow" wave). The MLSP method yielded estimates of attenuation slopes accurate to within 7% (polycarbonate plate) and 2% (cancellous bone phantom). The MLSP method yielded estimates of phase velocities accurate to within 1.5% (both media). The MLSP method was also tested on simulated data generated using attenuation slopes and phase velocities corresponding to bovine cancellous bone. Throughout broad ranges of signal-to-noise ratio (SNR), the MLSP method yielded estimates of attenuation slope that were accurate to within 1.0% and estimates of phase velocity that were accurate to within 4.3% (fast wave) and 1.3% (slow wave).
多孔介质（如松质骨）通常支持两种压缩波的同时传播。当使用宽带源对小骨样本进行透射检测时，这两种波通常会在时间上重叠。测试了改进的最小二乘 Prony （MLSP）方法，以分解包含两个重叠分量的 500 kHz 中心频率信号：一个通过聚碳酸酯板（产生“快”波），另一个通过松质骨模拟体（产生“慢”波）。MLSP 方法对衰减斜率的估计精度在 7%以内（聚碳酸酯板）和 2%以内（松质骨模拟体）。MLSP 方法对相位速度的估计精度在 1.5%以内（两种介质）。MLSP 方法还在使用与牛松质骨相对应的衰减斜率和相位速度生成的模拟数据上进行了测试。在广泛的信噪比（SNR）范围内，MLSP 方法对衰减斜率的估计精度在 1.0%以内，对相位速度的估计精度在 4.3%以内（快波）和 1.3%以内（慢波）。
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