Division of Critical Care, Marshall University, Huntington, WV 25701, USA.
Paediatr Respir Rev. 2010 Mar;11(1):46-53; quiz 53. doi: 10.1016/j.prrv.2009.10.008.
Helium-oxygen (heliox) gas mixtures have been studied for over 70 years as an adjunctive therapy for airway obstruction in a variety of respiratory diseases. The medical use of heliox is based on the physical properties of helium as its low density makes it advantageous in promoting more efficient flow through narrowed passages. Clinical evidence of the efficacy of heliox in treating paediatric respiratory diseases is increasing in the medical literature. This article consists of a comprehensive review of the literature investigating the utility of heliox in the treatment of paediatric respiratory disorders, including upper and lower airway obstruction, mechanical ventilation, and aerosol delivery.
氦-氧（heliox）混合气作为一种辅助治疗方法，已在多种呼吸系统疾病的气道阻塞中研究了 70 多年。氦氧的医疗用途基于氦的物理特性，因为其低密度有利于促进更有效的气流通过狭窄的通道。医学文献中越来越多的临床证据表明，氦氧在治疗儿科呼吸道疾病方面是有效的。本文对调查氦氧在治疗儿科呼吸道疾病（包括上呼吸道和下呼吸道阻塞、机械通气和气溶胶输送）中的应用的文献进行了全面回顾。
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